Active substance

Acetaminophen + Dextromethorphan Hydrobromide + Doxylamine Succinate + Phenylephrine Hydrochloride

3 products from 2 companies contain this in Canada.

3 without prescriptionliquidsyrup

Available without a prescription

NIGHTTIME COLD MEDICINE1000 mg + 30 mg + 12.5 mg + 10 mgWithout prescriptionliquid Jamp Pharma Corporation · Acetaminophen + Dextromethorphan Hydrobromide + Doxylamine Succinate + Phenylephrine Hydrochloride · N02BE51 NYQUIL COMPLETE650 mg + 20 mg + 12.5 mg + 10 mgWithout prescriptionsyrup Procter & Gamble Inc · Acetaminophen + Dextromethorphan Hydrobromide + Doxylamine Succinate + Phenylephrine Hydrochloride · N02BE51 VICKS NYQUIL COMPLETE COLD & FLU650 mg + 20 mg + 12.5 mg + 10 mgWithout prescriptionliquid Procter & Gamble Inc · Acetaminophen + Dextromethorphan Hydrobromide + Doxylamine Succinate + Phenylephrine Hydrochloride · N02BE51

Same substance is not the same product. Strength, form, release mechanism and other ingredients all differ. Whether one can replace another is a decision for a pharmacist.