Active substance

Acetaminophen + Guaifenesin + Pseudoephedrine Hydrochloride + Dextromethorphan Hydrobromide

2 products from 2 companies contain this in Canada.

2 without prescriptionsyrupcapsule

Available without a prescription

DAYTIME RELIEF COMPLETE250 mg + 100 mg + 30 mg + 10 mgWithout prescriptioncapsule Apotex Inc · Acetaminophen + Guaifenesin + Pseudoephedrine Hydrochloride + Dextromethorphan Hydrobromide · N02BE51 TOTAL COLD & FLU1000 mg + 200 mg + 60 mg + 30 mgWithout prescriptionsyrup Cellchem Pharmaceuticals Inc. · Acetaminophen + Guaifenesin + Pseudoephedrine Hydrochloride + Dextromethorphan Hydrobromide · N02BE51

Same substance is not the same product. Strength, form, release mechanism and other ingredients all differ. Whether one can replace another is a decision for a pharmacist.