Active substance

Acetaminophen + Phenylephrine Hydrochloride + Diphenhydramine Hydrochloride

2 products from 1 companies contain this in Canada.

2 without prescriptiontabletpowder for solution

Available without a prescription

COMPLETE ONE COLD AND FLU PE NIGHT325 mg + 5 mg + 25 mgWithout prescriptiontablet Cellchem Pharmaceuticals Inc. · Acetaminophen + Phenylephrine Hydrochloride + Diphenhydramine Hydrochloride · N02BE51 TOTAL COLD HOT LEMON RELIEF500 mg + 10 mg + 25 mgWithout prescriptionpowder for solution Cellchem Pharmaceuticals Inc. · Acetaminophen + Phenylephrine Hydrochloride + Diphenhydramine Hydrochloride · N02BE01

Same substance is not the same product. Strength, form, release mechanism and other ingredients all differ. Whether one can replace another is a decision for a pharmacist.