Active substance

Polymyxin B (Polymyxin B Sulfate) + Gramicidin

3 products from 2 companies contain this in Canada.

3 without prescriptiondropscream

Available without a prescription

OPTIMYXIN10000 unit + 0.025 mgWithout prescriptiondrops Euro-Pharm International Canada Inc · Polymyxin B (Polymyxin B Sulfate) + Gramicidin · S03AA30 POLYSPORIN ANTIBIOTIC CREAM10000 unit + 0.25 mgWithout prescriptioncream Kenvue Canada Inc. · Polymyxin B (Polymyxin B Sulfate) + Gramicidin · D06AX30 POLYSPORIN EYE AND EAR DROPS STERILE10000 unit + 0.025 mgWithout prescriptiondrops Kenvue Canada Inc. · Polymyxin B (Polymyxin B Sulfate) + Gramicidin · S03AA30

Same substance is not the same product. Strength, form, release mechanism and other ingredients all differ. Whether one can replace another is a decision for a pharmacist.