Medicine guide

COZAAR

As listed in the register: COZAAR

25 mg · tablet

  • Prescription only
  • Heart, blood pressure and circulation
Active substance
Losartan Potassium
Made by
Organon Canada Inc.

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupHeart, blood pressure and circulationC09CA01

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

From the US prescribing label for the same active substance (Losartan Potassium). It describes the substance, not this exact product.

Angiotensin II [formed from angiotensin I in a reaction catalyzed by angiotensin converting enzyme (ACE, kininase II)] is a potent vasoconstrictor, the primary vasoactive hormone of the renin-angiotensin system, and an important component in the pathophysiology of hypertension.

It also stimulates aldosterone secretion by the adrenal cortex.

Peak level after1 h
Half-life2 h
Mostly cleared after≈ 10 hfive half-lives — our arithmetic
PeakHalf gone10 h0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How it leaves the body

After single doses of losartan administered orally, about 4% of the dose is excreted unchanged in the urine and about 6% is excreted in urine as active metabolite.

With food

A meal slows absorption of losartan and decreases its C max but has only minor effects on losartan AUC or on the AUC of the metabolite (~10% decrease).

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-07-16

Safety of the active substance

From the US prescribing label for the same active substance (Losartan Potassium). It describes the substance, not this exact product.

Serious warning

WARNING: FETAL TOXICITY When pregnancy is detected, discontinue losartan potassium tablets as soon as possible.

Must not be used by
  • Losartan potassium tablets, are contraindicated:.
  • In patients who are hypersensitive to any component of this product..
  • For coadministration with aliskiren in patients with diabetes..
  • Hypersensitivity to any component.
Most common side effects

Most common adverse reactions (incidence ≥2% and greater than placebo) are: dizziness, upper respiratory infection, nasal congestion, and back pain.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

SwitzerlandNo exact match for this strength and form

Details

Made byOrganon Canada Inc.
Active substanceLosartan Potassium
Used inHeart, blood pressure and circulation
Strength25 mg
Formtablet
ClassificationC09CA01 · Heart, blood pressure and circulation
Routeoral
Dispensing (as stated by the register)PRESCRIPTION
StatusMarketed
MarketedYes, according to the register
DIN02182815
DPD drug code19167

Source: Drug Product Database · 2026-09-30 · not reviewed by a clinician

Contains information licensed under the Open Government Licence – Canada. Reuse terms: Open Government Licence – Canada.

Other strengths and forms

3 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.