FULVESTRANT INJECTION
As listed in the register: FULVESTRANT INJECTION
250 mg · solution
- Prescription only
- Cancer treatments and immune-system medicines
- Active substance
- Fulvestrant
- Made by
- Formative Pharma Inc.
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (CLIGAVYX). It describes the substance, not this exact product.
Many breast cancers have estrogen receptors (ER) and the growth of these tumors can be stimulated by estrogen.
Fulvestrant is an estrogen receptor antagonist that binds to the estrogen receptor in a competitive manner with affinity comparable to that of estradiol and downregulates the ER protein in human breast cancer cells.
Although fulvestrant is partly metabolized by CYP 3A4, a clinical study with rifampin, an inducer of CYP 3A4, showed no effect on the pharmacokinetics of fulvestrant.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-06-24
Safety of the active substance
From the US prescribing label for the same active substance (CLIGAVYX). It describes the substance, not this exact product.
- CLIGAVYX is contraindicated in patients with a known hypersensitivity to the drug or to any of its components.
- Hypersensitivity reactions, including urticaria and angioedema, have been reported in association with CLIGAVYX [see Adverse Reactions (6.2) ].
The most frequently reported adverse reactions in the fulvestrant 500 mg group were injection site pain (11.6% of patients), nausea (9.7% of patients), and bone pain (9.4% of patients); the most frequently reported adverse reactions in the fulvestrant 250 mg group were nausea (13.6% of patients), back pain (10.7% of patients), and injection site pain (9.1% of patients).
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
European UnionNo exact match for this strength and form
SpainNo exact match for this strength and form
FranceNo exact match for this strength and form
NetherlandsNo exact match for this strength and form
SwitzerlandNo exact match for this strength and form
Details
| Made by | Formative Pharma Inc. |
|---|---|
| Active substance | Fulvestrant |
| Used in | Cancer treatments and immune-system medicines |
| Strength | 250 mg |
| Form | solution |
| Classification | L02BA03 · Cancer treatments and immune-system medicines |
| Route | intramuscular |
| Dispensing (as stated by the register) | PRESCRIPTION |
| Status | Marketed |
| Marketed | Yes, according to the register |
| DIN | 02536293 |
| DPD drug code | 102508 |
Source: Drug Product Database · 2026-09-30 · not reviewed by a clinician
Contains information licensed under the Open Government Licence – Canada. Reuse terms: Open Government Licence – Canada.
Other strengths and forms
5 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- solution5 products
250 mg5
250 mg · 5 companies
- Auro Pharma Inc
- Eugia Pharma Inc.
- Formative Pharma Inc. · this page
- Sandoz Canada Incorporated
- Sterimax Inc
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.