METFORMIN TABLETS
As listed in the register: METFORMIN TABLETS
500 mg · tablet
- Prescription only
- Digestion, stomach, diabetes and nutrition
- Active substance
- Metformin Hydrochloride
- Made by
- Apotex Inc
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (metformin hydrochloride). It describes the substance, not this Bulgarian product — its uses and doses can differ.
Metformin is an antihyperglycemic agent which improves glucose tolerance in patients with type 2 diabetes mellitus, lowering both basal and postprandial plasma glucose.
Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
Intravenous single-dose studies in normal subjects demonstrate that metformin is excreted unchanged in the urine and does not undergo hepatic metabolism (no metabolites have been identified in humans) nor biliary excretion.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-01-01
Safety of the active substance
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (metformin hydrochloride). It describes the substance, not this Bulgarian product — its uses and doses can differ.
WARNING: LACTIC ACIDOSIS Postmarketing cases of metformin-associated lactic acidosis have resulted in death, hypothermia, hypotension, and resistant bradyarrhythmias.
- Metformin hydrochloride tablets are contraindicated in patients with: Severe renal impairment (eGFR below 30 mL/min/1.73 m 2 ) [see Warnings and Precautions (5.1) ].
- Hypersensitivity to metformin.
- Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.
- Severe renal impairment (eGFR below 30 mL/min/1.73 m 2 ) ( 4, 5.1 ) Hypersensitivity to metformin ( 4 ) Acute or chronic metabolic acidosis, including diabetic ketoacidosis, with or without coma.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United States122 matching products
- Metformin Hydrochloride 500 mg · Tablet, Film Coated, Extended Release99 makers
- Metformin Hcl 500 mg · Tablet12 makers
- Metformin Hydrochloride Extended Release 500 mg · Tablet, Extended Release7 makers
- Glumetza 500 mg · Tablet, Film Coated, Extended Release
- Metformin 500 mg · Tablet, Extended Release
- Metformin Hydrochloride Er 500 mg · Tablet, Extended Release
- Metformin Hydrochloride Extended-Release 500mg 500 mg · Tablet, Extended Release
Bulgaria19 matching products
- Glucophage 500 mg film-coated tablets blisters · film - coated tablets2 makers
- Brotmin 500 mg · film - coated tablets
- Glucophage XR 500 mg · prolonged - release tablets
- Insufor 500 mg film-coated tablets · film-coated tablets
- Meglucon XR 500 mg · prolonged - release tablets
- Metfocon XR 500 mg · prolonged - release tablets
- Metfodiab 500 mg film-coated tablets blisters · film - coated tablets
- Metfogamma 500 mg film - coated tablets · film coated tablet
Spain6 matching products
- BROTMIN 500 mg · comprimido recubierto con película
- METFORMINA ACTIVASE 500 mg · comprimido recubierto con película
- METFORMINA ADAIR 500 mg · comprimido recubierto con película
- METFORMINA ALTER 500 mg · comprimido recubierto con película
- METFORMINA BIOFARM 500 MG · comprimido recubierto con película
- METFORMINA CINFAMED 500 mg · comprimido recubierto con película
Netherlands10 matching products
- Metformine HCl Aurobindo 500 mg 500 mg · filmomhulde tablet2 makers
- Glucient SR 500 mg 500 mg · tablet met verlengde afgifte
- Metformine HCl 1A Pharma tablet 500 mg 500 mg · filmomhulde tablet
- Metformine HCl 500 mg Teva 500 mg · filmomhulde tablet
- Metformine HCl Accord 500 mg filmomhulde tabletten 500 mg · filmomhulde tablet
- Metformine HCl Activase 500 mg 500 mg · filmomhulde tablet
- Metformine HCl Sandoz 500 mg 500 mg · filmomhulde tablet
- Metformine HCl Viatris 500 mg 500 mg · filmomhulde tablet
SwitzerlandNo exact match for this strength and form
Details
| Made by | Apotex Inc |
|---|---|
| Active substance | Metformin Hydrochloride |
| Used in | Digestion, stomach, diabetes and nutrition |
| Strength | 500 mg |
| Form | tablet |
| Classification | A10BA02 · Digestion, stomach, diabetes and nutrition |
| Route | oral |
| Dispensing (as stated by the register) | PRESCRIPTION |
| Status | Dormant |
| Marketed | No — authorised but not currently marketed, according to the register |
| DIN | 02527650 |
| DPD drug code | 101670 |
Source: Drug Product Database · 2026-09-30 · not reviewed by a clinician
Contains information licensed under the Open Government Licence – Canada. Reuse terms: Open Government Licence – Canada.
Other strengths and forms
6 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- tablet6 products
500 mg3
500 mg · 3 companies
- Apotex Inc · this page
- Granules India Limited
- Sanis Health Inc
850 mg3
850 mg · 3 companies
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.