PMS-BUSULFAN
As listed in the register: PMS-BUSULFAN
6 mg · solution
- Prescription only
- Cancer treatments and immune-system medicines
- Active substance
- Busulfan
- Made by
- Pharmascience Inc
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (MYLERAN). It describes the substance, not this exact product.
Busulfan is a small, highly lipophilic molecule that easily crosses the blood brain barrier.
Following absorption, 32% and 47% of busulfan are bound to plasma proteins and red blood cells, respectively.
This probably reflects the extensive metabolism of the drug in the liver, since less than 2% of the administered dose is excreted in the urine unchanged within 24 hours.
Currently, there are no available data on the effect of food on busulfan bioavailability.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-01-08
Safety of the active substance
From the US prescribing label for the same active substance (MYLERAN). It describes the substance, not this exact product.
WARNING MYLERAN is a potent drug.
- MYLERAN is contraindicated in patients in whom a definitive diagnosis of chronic myelogenous leukemia has not been firmly established.
- MYLERAN is contraindicated in patients who have previously suffered a hypersensitivity reaction to busulfan or any other component of the preparation.
The most frequent, serious, toxic effect of busulfan is dose-related myelosuppression resulting in leukopenia, thrombocytopenia, and anemia.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
European UnionNo exact match for this strength and form
SpainNo exact match for this strength and form
FranceNo exact match for this strength and form
NetherlandsNo exact match for this strength and form
Details
| Made by | Pharmascience Inc |
|---|---|
| Active substance | Busulfan |
| Used in | Cancer treatments and immune-system medicines |
| Strength | 6 mg |
| Form | solution |
| Classification | L01AB01 · Cancer treatments and immune-system medicines |
| Route | intravenous |
| Dispensing (as stated by the register) | PRESCRIPTION |
| Status | Marketed |
| Marketed | Yes, according to the register |
| DIN | 02477343 |
| DPD drug code | 96833 |
Source: Drug Product Database · 2026-09-30 · not reviewed by a clinician
Contains information licensed under the Open Government Licence – Canada. Reuse terms: Open Government Licence – Canada.
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.