Medicine guide

PONVORY

As listed in the register: PONVORY

20 mg · tablet

  • Prescription only
  • Cancer treatments and immune-system medicines
Active substance
Ponesimod
Made by
Vanda Pharmaceuticals Inc.

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupCancer treatments and immune-system medicinesL04AE04

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

From the US prescribing label for the same active substance (PONVORY). It describes the substance, not this exact product.

Ponesimod is a S1P receptor 1 modulator that binds with high affinity to S1P receptor 1.

Ponesimod blocks the capacity of lymphocytes to egress from lymph nodes, reducing the number of lymphocytes in peripheral blood.

Peak level after2–4 h
Half-life33 h
Mostly cleared after≈ 7 daysfive half-lives — our arithmetic
PeakHalf gone7 days0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

Ponesimod is extensively metabolized prior to excretion in humans, though unchanged ponesimod was the main circulating component in plasma.

With food

Food Effect Food does not have a clinically relevant effect on ponesimod pharmacokinetics; therefore, PONVORY may be taken with or without food.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-12-04

Safety of the active substance

From the US prescribing label for the same active substance (PONVORY). It describes the substance, not this exact product.

Most common side effects

The most common adverse reactions (incidence at least 10%) in PONVORY-treated patients in Study 1 were upper respiratory tract infection, hepatic transaminase elevation, and hypertension.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

European UnionNo exact match for this strength and form

SwitzerlandNo exact match for this strength and form

Details

Made byVanda Pharmaceuticals Inc.
Active substancePonesimod
Used inCancer treatments and immune-system medicines
Strength20 mg
Formtablet
ClassificationL04AE04 · Cancer treatments and immune-system medicines
Routeoral
Dispensing (as stated by the register)PRESCRIPTION
StatusMarketed
MarketedYes, according to the register
DIN02515482
DPD drug code100487

Source: Drug Product Database · 2026-09-30 · not reviewed by a clinician

Contains information licensed under the Open Government Licence – Canada. Reuse terms: Open Government Licence – Canada.

Other strengths and forms

2 products are sold under this name. Grouped by form; a number on a strength means several companies make it.