Medicine guide

PROSTIGMIN

As listed in the register: PROSTIGMIN

15 mg · tablet

  • Prescription only
  • Pain, sleep, mood, epilepsy and the brain
Active substance
Neostigmine Bromide
Made by
Bausch Health, Canada Inc.

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupPain, sleep, mood, epilepsy and the brainN07AA01

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

From the US prescribing label for the same active substance (Neostigmine). It describes the substance, not this exact product.

Neostigmine methylsulfate is a competitive cholinesterase inhibitor.

By reducing the breakdown of acetylcholine, neostigmine methylsulfate induces an increase in acetylcholine in the synaptic cleft which competes for the same binding site as nondepolarizing neuromuscular blocking agents, and reverses the neuromuscular blockade.

Half-life24–113 min
Mostly cleared after≈ 5.7 hfive half-lives — our arithmetic
How the body breaks it down

Neostigmine methylsulfate is metabolized by microsomal enzymes in the liver.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2023-05-15

Safety of the active substance

From the US prescribing label for the same active substance (Neostigmine). It describes the substance, not this exact product.

Must not be used by
  • Hypersensitivity to neostigmine (4).
  • Peritonitis or mechanical obstruction of the intestinal or urinary tract (4)
Most common side effects

Most common adverse reactions during treatment: bradycardia, nausea and vomiting ( 6) To report SUSPECTED ADVERSE REACTIONS, contact Dr.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

United StatesNo exact match for this strength and form

SpainNo exact match for this strength and form

NetherlandsNo exact match for this strength and form

Details

Made byBausch Health, Canada Inc.
Active substanceNeostigmine Bromide
Used inPain, sleep, mood, epilepsy and the brain
Strength15 mg
Formtablet
ClassificationN07AA01 · Pain, sleep, mood, epilepsy and the brain
Routeoral
Dispensing (as stated by the register)PRESCRIPTION
StatusDormant
MarketedNo — authorised but not currently marketed, according to the register
DIN00869945
DPD drug code11691

Source: Drug Product Database · 2026-09-30 · not reviewed by a clinician

Contains information licensed under the Open Government Licence – Canada. Reuse terms: Open Government Licence – Canada.