TRANDATE
As listed in the register: TRANDATE
100 mg · tablet
- Prescription only
- Heart, blood pressure and circulation
- Active substance
- Labetalol Hydrochloride
- Made by
- Knight Therapeutics Inc.
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Labetalol Hydrochloride). It describes the substance, not this exact product.
Labetalol hydrochloride combines both selective, competitive, alpha 1 -adrenergic blocking and nonselective, competitive, beta-adrenergic blocking activity in a single substance.
In man, the ratios of alpha- to beta-blockade have been estimated to be approximately 1:3 and 1:7 following oral and intravenous (IV) administration, respectively.
These metabolites are present in plasma and are excreted in the urine and, via the bile, into the feces.
The absolute bioavailability of labetalol is increased when administered with food.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2024-10-07
Safety of the active substance
From the US prescribing label for the same active substance (Labetalol Hydrochloride). It describes the substance, not this exact product.
- Labetalol hydrochloride is contraindicated in bronchial asthma, overt cardiac failure, greater-than-first- degree heart block, cardiogenic shock, severe bradycardia, other conditions associated with severe and prolonged hypotension, and in patients with a history of hypersensitivity to any component of the product [see Warnings ].
- Beta-blockers, even those with apparent cardioselectivity, should not be used in patients with a history of obstructive airway disease, including asthma.
Most frequently described as scalp tingling.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United States30 matching products
Spain1 matching products
Netherlands1 matching products
SwitzerlandNo exact match for this strength and form
Details
| Made by | Knight Therapeutics Inc. |
|---|---|
| Active substance | Labetalol Hydrochloride |
| Used in | Heart, blood pressure and circulation |
| Strength | 100 mg |
| Form | tablet |
| Classification | C07AG01 · Heart, blood pressure and circulation |
| Route | oral |
| Dispensing (as stated by the register) | PRESCRIPTION |
| Status | Marketed |
| Marketed | Yes, according to the register |
| DIN | 02106272 |
| DPD drug code | 29542 |
Source: Drug Product Database · 2026-09-30 · not reviewed by a clinician
Contains information licensed under the Open Government Licence – Canada. Reuse terms: Open Government Licence – Canada.
Other strengths and forms
2 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- tablet2 products
- 100 mg
- 200 mg
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.