YONDELIS
As listed in the register: YONDELIS
1 mg · powder for solution
- Prescription only
- Cancer treatments and immune-system medicines
- Active substance
- Trabectedin
- Made by
- Valeo Pharma Inc
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (EVDI). It describes the substance, not this exact product.
Trabectedin is an alkylating drug that binds guanine residues in the minor groove of DNA, forming adducts and resulting in a bending of the DNA helix towards the major groove.
Adduct formation triggers a cascade of events that can affect the subsequent activity of DNA binding proteins, including some transcription factors, and DNA repair pathways, resulting in perturbation of the cell cycle and eventual cell death.
Trabectedin was extensively metabolized with negligible unchanged drug in urine and feces following administration of trabectedin to humans.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-06-29
Safety of the active substance
From the US prescribing label for the same active substance (EVDI). It describes the substance, not this exact product.
- EVDI is contraindicated in patients with known severe hypersensitivity, including anaphylaxis, to trabectedin.
- Known hypersensitivity to trabectedin ( 4 )
The most common (≥5%) grades 3 to 4 laboratory abnormalities are: neutropenia, increased ALT, thrombocytopenia, anemia, increased AST, and increased creatine phosphokinase.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
European UnionNo exact match for this strength and form
SpainNo exact match for this strength and form
NetherlandsNo exact match for this strength and form
SwitzerlandNo exact match for this strength and form
Details
| Made by | Valeo Pharma Inc |
|---|---|
| Active substance | Trabectedin |
| Used in | Cancer treatments and immune-system medicines |
| Strength | 1 mg |
| Form | powder for solution |
| Classification | L01CX01 · Cancer treatments and immune-system medicines |
| Route | intravenous |
| Dispensing (as stated by the register) | PRESCRIPTION |
| Status | Marketed |
| Marketed | Yes, according to the register |
| DIN | 02351528 |
| DPD drug code | 83679 |
Source: Drug Product Database · 2026-09-30 · not reviewed by a clinician
Contains information licensed under the Open Government Licence – Canada. Reuse terms: Open Government Licence – Canada.
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.