PAZOPANIB ACCORD
As listed in the register: PAZOPANIB ACCORD 400 MG COMPRIMIDOS RECUBIERTOS CON PELÍCULA EFG
400 mg · comprimido recubierto con película
- Prescription only
- Cancer treatments and immune-system medicines
- Active substance
- Pazopanib
- Made by
- Accord Healthcare S.L.U.
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (pazopanib). It describes the substance, not this Bulgarian product — its uses and doses can differ.
In vitro, pazopanib inhibited ligand-induced autophosphorylation of VEGFR-2, Kit, and PDGFR-β receptors.
In vivo, pazopanib inhibited VEGF-induced VEGFR-2 phosphorylation in mouse lungs, angiogenesis in a mouse model, and the growth of some human tumor xenografts in mice.
In vitro studies demonstrated that pazopanib is metabolized by CYP3A4 with a minor contribution from CYP1A2 and CYP2C8.
Effect of Food Systemic exposure to pazopanib is increased when administered with food.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-01-19
Safety of the active substance
This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (pazopanib). It describes the substance, not this Bulgarian product — its uses and doses can differ.
WARNING: HEPATOTOXICITY Severe and fatal hepatotoxicity has been observed in clinical trials.
The most common adverse reactions in patients with STS (≥ 20%) are fatigue, diarrhea, nausea, decreased weight, hypertension, decreased appetite, vomiting, tumor pain, hair color changes, musculoskeletal pain, headache, dysgeusia, dyspnea, and skin hypopigmentation.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
Bulgaria8 matching products
- Pazopanib G.L. Pharma 400 mg · film-coated tablets2 makers
- Alunib 400 mg · film-coated tablets
- PazoFront 400 mg · film-coated tablets
- Pazopanib Accord 400 mg · film-coated tablets
- Pazopanib Pharmascience 400 mg · film-coated tablets
- Pazopanib Teva 400 mg · film-coated tablets
- Pazopanib Zentiva 400 mg · film-coated tablets
European UnionNo exact match for this strength and form
CanadaNo exact match for this strength and form
Netherlands8 matching products
- Pazopanib Accord 400 mg filmomhulde tabletten 400 mg · filmomhulde tablet
- Pazopanib CF 400 mg 400 mg · filmomhulde tablet
- Pazopanib Devatis 400 mg filmomhulde tabletten 400 mg · filmomhulde tablet
- Pazopanib Glenmark 400 mg filmomhulde tabletten 400 mg · filmomhulde tablet
- Pazopanib Reddy 400 mg filmomhulde tabletten 400 mg · filmomhulde tablet
- Pazopanib Teva 400 mg 400 mg · filmomhulde tablet
- Pazopanib Viatris 400 mg 400 mg · filmomhulde tablet
- Votrient 400 mg 400 mg · filmomhulde tablet
SwitzerlandNo exact match for this strength and form
Details
| Made by | Accord Healthcare S.L.U. |
|---|---|
| Active substance | Pazopanib |
| Used in | Cancer treatments and immune-system medicines |
| Strength | 400 mg |
| Form | comprimido recubierto con película |
| Classification | L01EX03 · Cancer treatments and immune-system medicines |
| Route | vía oral |
| Marketed | Yes, according to the register |
| Generic | Yes — a generic medicine, according to the register |
| Name in the register | PAZOPANIB ACCORD 400 MG COMPRIMIDOS RECUBIERTOS CON PELÍCULA EFG |
| Nº Registro | 89351 |
Source: CIMA — Centro de Información online de Medicamentos · 2026-09-30 · not reviewed by a clinician
Fuente: Agencia Española de Medicamentos y Productos Sanitarios (AEMPS), CIMA. Reuse terms: Aviso legal AEMPS.
Other strengths and forms
2 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- comprimido recubierto con película2 products
- 200 mg
- 400 mg
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.