Medicine guide

Ranexa (previously Latixa)

  • Prescription status not stated
  • Heart, blood pressure and circulation
Active substance
Ranolazine
Made by
Menarini International Operations Luxembourg S.A. (MIOL)

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

  • Ranexa is indicated as add-on therapy for the symptomatic treatment of patients with stable angina pectoris who are inadequately controlled or intolerant to first-line anti-anginal therapies (such as beta-blockers and / or calcium antagonists).

From the official label · 2026-09-30 · European Medicines Agency

How it works

From the US prescribing label for the same active substance (Ranolazine). It describes the substance, not this exact product.

The mechanism of action of ranolazine’s antianginal effects has not been determined.

Ranolazine has anti-ischemic and antianginal effects that do not depend upon reductions in heart rate or blood pressure.

Peak level after2–5 h
Half-life7 h
Mostly cleared after≈ 35 hfive half-lives — our arithmetic
PeakHalf gone35 h0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

Ranolazine is extensively metabolized in the gut and liver and its absorption is highly variable.

How it leaves the body

Following a single oral dose of ranolazine solution, approximately 75% of the dose is excreted in urine and 25% in feces.

With food

The pharmacokinetics of ranolazine is unaffected by age, gender, or food.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-19

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

United StatesNo exact match for this strength and form

SpainNo exact match for this strength and form

FranceNo exact match for this strength and form

CanadaNo exact match for this strength and form

NetherlandsNo exact match for this strength and form

SwitzerlandNo exact match for this strength and form

Details

Made byMenarini International Operations Luxembourg S.A. (MIOL)
Active substanceRanolazine
Used inHeart, blood pressure and circulation
ClassificationC01EB18 · Heart, blood pressure and circulation
Authorised on2008-07-08
Last updated by the regulator2024-04-10
EMA product numberEMEA/H/C/000805

Source: European Medicines Agency — medicine data · 2026-09-30 · not reviewed by a clinician

Source: European Medicines Agency (EMA). Product information as published by EMA. Reuse terms: EMA legal notice (reproduction authorised).