Verkazia
- Prescription status not stated
- Eyes and ears
- Active substance
- Ciclosporin
- Used in
- Eyes and ears
- Made by
- Santen Oy
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
- Treatment of severe vernal keratoconjunctivitis (VKC) in children from 4 years of age and adolescents.
From the official label · 2026-09-30 · European Medicines Agency
How it works
From the US prescribing label for the same active substance (CycloSPORINE, Modfied). It describes the substance, not this exact product.
Cyclosporine is a potent immunosuppressive agent that in animals prolongs survival of allogeneic transplants involving skin, kidney, liver, heart, pancreas, bone marrow, small intestine, and lung.
Cyclosporine has been demonstrated to suppress some humoral immunity and to a greater extent, cell-mediated immune reactions such as allograft rejection, delayed hypersensitivity, experimental allergic encephalomyelitis, Freund’s adjuvant arthritis, and graft versus host disease in many animal species for a variety of organs.
Cyclosporine is extensively metabolized by the cytochrome P-450 3A enzyme system in the liver, and to a lesser degree in the gastrointestinal tract, and the kidney.
Elimination of cyclosporine is primarily biliary with only 6% of the dose (parent drug and metabolites) excreted in urine.
The administration of food with cyclosporine capsule (modified) decreases the cyclosporine AUC and C max.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-09-10
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
SpainNo exact match for this strength and form
CanadaNo exact match for this strength and form
NetherlandsNo exact match for this strength and form
SwitzerlandNo exact match for this strength and form
Details
| Made by | Santen Oy |
|---|---|
| Active substance | Ciclosporin |
| Used in | Eyes and ears |
| Classification | S01XA18 · Eyes and ears |
| Orphan medicine | Yes — designated for a rare disease, according to the register |
| Authorised on | 2018-07-06 |
| Last updated by the regulator | 2026-01-15 |
| EMA product number | EMEA/H/C/004411 |
Source: European Medicines Agency — medicine data · 2026-09-30 · not reviewed by a clinician
Source: European Medicines Agency (EMA). Product information as published by EMA. Reuse terms: EMA legal notice (reproduction authorised).
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.