Medicine guide

Jevtana

  • Prescription status not stated
  • Cancer treatments and immune-system medicines
Active substance
Cabazitaxel
Made by
Sanofi Winthrop Industrie

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

  • Jevtana in combination with prednisone or prednisolone is indicated for the treatment of patients with hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing regimen.

From the official label · 2026-09-30 · European Medicines Agency

How it works

From the US prescribing label for the same active substance (Jevtana). It describes the substance, not this exact product.

Cabazitaxel is a microtubule inhibitor.

Cabazitaxel binds to tubulin and promotes its assembly into microtubules while simultaneously inhibiting disassembly.

How the body breaks it down

Cabazitaxel is extensively metabolized in the liver (>95%), mainly by the CYP3A4/5 isoenzyme (80% to 90%), and to a lesser extent by CYP2C8.

How it leaves the body

Around 20 metabolites of cabazitaxel are excreted into human urine and feces.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-10-07

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

United StatesNo exact match for this strength and form

SpainNo exact match for this strength and form

FranceNo exact match for this strength and form

CanadaNo exact match for this strength and form

NetherlandsNo exact match for this strength and form

Details

Made bySanofi Winthrop Industrie
Active substanceCabazitaxel
Used inCancer treatments and immune-system medicines
ClassificationL01CD · Cancer treatments and immune-system medicines
Authorised on2011-03-17
Last updated by the regulator2025-09-30
EMA product numberEMEA/H/C/002018

Source: European Medicines Agency — medicine data · 2026-09-30 · not reviewed by a clinician

Source: European Medicines Agency (EMA). Product information as published by EMA. Reuse terms: EMA legal notice (reproduction authorised).

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.