Medicine guide

Jylamvo

  • Prescription status not stated
  • Cancer treatments and immune-system medicines
Active substance
Methotrexate
Made by
Oresund Pharma ApS

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

  • In rheumatological and dermatological diseases Active rheumatoid arthritis in adult patients. Polyarthritic forms of active, severe juvenile idiopathic arthritis (JIA) in adolescents and children aged 3 years and over when the response to non-steroidal anti-inflammatory drugs (NSAIDs) has been inadequate. Severe, treatment-refractory, disabling psoriasis which does not respond sufficiently to other forms of treatment such as phototherapy, psoralen and ultraviolet A radiation (PUVA) therapy and retinoids, and severe psoriatic arthritis in adult patients. In oncology Maintenance treatment of acute lymphoblastic leukaemia (ALL) in adults, adolescents and children aged 3 years and over.

From the official label · 2026-09-30 · European Medicines Agency

How it works

From the US prescribing label for the same active substance (Methotrexate). It describes the substance, not this exact product.

Methotrexate inhibits dihydrofolic acid reductase.

Dihydrofolates must be reduced to tetrahydrofolates by this enzyme before they can be utilized as carriers of one-carbon groups in the synthesis of purine nucleotides and thymidylate.

Peak level after0.75–6 h
Half-life3–10 h
Mostly cleared after≈ 32.5 hfive half-lives — our arithmetic
PeakHalf gone32.5 h0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

Methotrexate is partially metabolized by intestinal flora after oral administration.

With food

Effect of Food Food has been shown to delay absorption and reduce peak concentration.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-27

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

United StatesNo exact match for this strength and form

SpainNo exact match for this strength and form

CanadaNo exact match for this strength and form

NetherlandsNo exact match for this strength and form

SwitzerlandNo exact match for this strength and form

Details

Made byOresund Pharma ApS
Active substanceMethotrexate
Used inCancer treatments and immune-system medicines
ClassificationL04AX03 · Cancer treatments and immune-system medicines
Authorised on2017-03-29
Last updated by the regulator2026-09-07
EMA product numberEMEA/H/C/003756

Source: European Medicines Agency — medicine data · 2026-09-30 · not reviewed by a clinician

Source: European Medicines Agency (EMA). Product information as published by EMA. Reuse terms: EMA legal notice (reproduction authorised).

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.