Lacosamide Accord

Do not take it if

From the package leaflet in EMA’s product information, p. 94–95.

How to take it

These directions are for this exact strength and form. Another one is different.

• Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. Other form(s) of this medicine may be more suitable for children;
• ask your doctor or pharmacist.
• Taking Lacosamide Accord
• Take Lacosamide Accord twice each day- approximately 12 hours apart. Try to take it at about the same time each day.
• Swallow the Lacosamide Accord tablet with a glass of water.
• You may take Lacosamide Accord with or without food.
• You will usually start by taking a low dose each day and your doctor will slowly increase this over a number of weeks. When you reach the dose that works for you, this is called the “maintenance dose”, you then take the same amount each day. Lacosamide Accord is used as a long term treatment. You should continue to take Lacosamide Accord until your doctor tells you to stop.
• How much to take Listed below are the normal recommended doses of Lacosamide Accord for different age groups and weights. Your doctor may prescribe a different dose if you have problems with your kidneys or with your liver.
• Adolescents and children weighing 50 kg or more and adults When you take Lacosamide Accord on its own The usual starting dose of Lacosamide Accord is 50 mg twice a day.
• Your doctor may also prescribe a starting dose of 100 mg of Lacosamide Accord twice a day.
• Your doctor may increase your twice daily dose every week by 50 mg. This will be until you reach a maintenance dose between 100 mg and 300 mg twice a day.
• When you take Lacosamide Accord with other antiepileptic medicines The usual starting dose of Lacosamide Accord is 50 mg twice a day.
• Your doctor may increase your twice daily dose every week by 50 mg. This will be until you reach a maintenance dose between 100 mg and 200 mg twice a day.
• If you weigh 50 kg or more, your doctor may decide to start Lacosamide Accord treatment with a single “loading” dose of 200 mg. You would then start your ongoing maintenance dose 12 hours later.
• Children and adolescents weighing less than 50 kg
• In the treatment of partial-onset seizure: Observe that Lacosamide Accord is not recommended for children under 2 years of age.
• In the treatment of primary generalised tonic-clonic seizures: Observe that Lacosamide Accord is not recommended for children under 4 years of age.
• The dose depends on their body weight. They usually start treatment with the syrup and only change to tablets if they are able to take tablets and get the correct dose with the different tablet strengths. The doctor will prescribe the formulation that is best suited to them.
• If you take more Lacosamide Accord than you should If you have taken more Lacosamide Accord than you should, contact your doctor immediately. Do not try to drive.
• You may experience:
• dizziness;
• feeling sick (nausea) or being sick (vomiting);
• fits (seizures), heart beat problems such a slow, fast or irregular heart beat, coma or a fall in blood pressure with rapid heartbeat and sweating.
• If you forget to take Lacosamide Accord
• If you have missed a dose within the first 6 hours of the scheduled dose, take it as soon as you remember.
• If you have missed a dose beyond the first 6 hours of the scheduled dose, do not take the missed tablet anymore. Instead take Lacosamide Accord at the next time that you would normally take it.
• Do not take a double dose to make up for a forgotten dose.
• If you stop taking Lacosamide Accord
• Do not stop taking Lacosamide Accord without talking to your doctor, as your epilepsy may come back again or become worse.
• If your doctor decides to stop your treatment with Lacosamide Accord , they will tell you how to decrease the dose step by step.
• If you have any further questions on the use of this medicine, ask your doctor or pharmacist.

From the package leaflet in EMA’s product information, p. 96–97.

Warnings and precautions

From the package leaflet in EMA’s product information, p. 95.

Pregnancy and breastfeeding

From the package leaflet in EMA’s product information, p. 96.

Other medicines

From the package leaflet in EMA’s product information, p. 95–96.

Driving and using machines

• Do not drive, cycle or use any tools or machines until you know how this medicine affects you. This is because Lacosamide Accord may make you feel dizzy or cause blurred vision.
• Lacosamide Accord contains soya lecithin.
• If you are allergic to peanut or soya, do not use this medicinal product.

From the package leaflet in EMA’s product information, p. 96.

Side effects

• Like all medicines, this medicine can cause side effects, although not everybody gets them.
• Nervous system side effects such as dizziness may be higher after a single “loading” dose.
• Talk to your doctor or pharmacist if you get any of the following:
• Very common: may affect more than 1 in 10 people
• Headache;
• Feeling dizzy or sick (nausea);
• Double vision (diplopia).
• Common: may affect up to 1 in 10 people
• Short jerks of a muscle or group of muscles (myoclonic seizures);
• Difficulties in coordinating your movements or walking;
• Problems in keeping your balance, shaking (tremor), tingling (paresthesia) or muscle spasms, falling easily and getting bruises;
• Troubles with your memory, thinking or finding words, confusion;
• Rapid and uncontrollable movements of the eyes (nystagmus), blurred vision;
• A spinning sensation (vertigo), feeling drunk;
• Being sick (vomiting), dry mouth, constipation, indigestion, excessive gas in the stomach or bowel, diarrhoea;
• Decreased feeling or sensitivity, difficulty in articulating words, disturbance in attention
• Noise in the ear such as buzzing, ringing or whistling
• Irritability, trouble sleeping, depression;
• Sleepiness, tiredness or weakness (asthenia);
• Itching, rash.
• Uncommon: may affect up to 1 in 100 people
• Slow heart rate, palpitations, irregular pulse or other changes in the electrical activity of your heart (conduction disorder);
• Exaggerated feeling of wellbeing, seeing and/or hearing things which are not there;
• Allergic reaction to medicine intake, hives;
• Blood tests may show abnormal liver function, liver injury;
• Thoughts of harming or killing yourself or attempting suicide: tell your doctor straight away;
• Feeling angry or agitated;
• Abnormal thinking or losing touch with reality;
• Serious allergic reaction which causes swelling of the face, throat, hands, feet, ankles, or lower legs;
• Fainting.
• Abnormal involuntary movements (dyskinesia).
• Not known: frequency cannot be estimated from available data
• Abnormal rapid heartbeat (ventricular tachyarrhythmia);
• A sore throat, high temperature and getting more infections than usual. Blood tests may show a severe decrease in a specific class of white blood cells (agranulocytosis);
• A serious skin reaction which may include a high temperature and other flu-like symptoms, a rash on the face, extended rash, swollen glands (enlarged lymph nodes). Blood tests may show increased levels of liver enzymes and a type of white blood cell (eosinophilia);
• A widespread rash with blisters and peeling skin, particularly around the mouth, nose, eyes and genitals (Stevens–Johnson syndrome), and a more severe form causing skin peeling in more than 30 % of the body surface (toxic epidermal necrolysis);
• Convulsion.
• Additional side effects in children The additional side effects in children were runny nose (nasopharyngitis), fever (pyrexia), sore throat (pharyngitis), eating less than usual (decreased appetite), changes in behaviour, not acting like themselves (abnormal behavior) and lacking in energy (lethargy). Feeling sleepy (somnolence) is a very common side effect in children and may affect more than 1 in 10 children.
• Reporting of side effects If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects you can help provide more information on the safety of this medicine.

From the package leaflet in EMA’s product information, p. 97–99.

How to store it

• Keep this medicine out of the sight and reach of children.
• Do not use this medicine after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of that month.
• This medicine does not require any special storage conditions.
• Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to throw away medicines you no longer use. These measures will help protect the environment.

From the package leaflet in EMA’s product information, p. 99.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

• The other ingredients are:
• Tablet core: Microcrystalline cellulose, hydroxy propyl cellulose-L, hydroxy propyl cellulose (low substituted), silica colloidal anhydrous, crospovidone and magnesium stearate.
• Film-coat: Polyvinyl alcohol, polyethylene glycol, talc, titanium dioxide (E171), lecithin (soya) and colorants*

From the package leaflet in EMA’s product information, p. 99.

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

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Details

Source: European Medicines Agency — medicine data · 2026-09-30 · not reviewed by a clinician

Source: European Medicines Agency (EMA). Product information as published by EMA. Reuse terms: EMA legal notice (reproduction authorised).

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Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.

See every product with Lacosamide