Medicine guide

Yorvipath

  • Prescription status not stated
  • Hormones, such as thyroid and steroids
Active substance
Palopegteriparatide
Made by
Ascendis Pharma Bone Diseases A/S

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

  • Yorvipath is a parathyroid hormone (PTH) replacement therapy indicated for the treatment of adults with chronic hypoparathyroidism

From the official label · 2026-09-30 · European Medicines Agency

How it works

From the US prescribing label for the same active substance (Yorvipath). It describes the substance, not this exact product.

At physiological conditions, palopegteriparatide releases PTH(1-34) to maintain a continuous systemic exposure.

Endogenous PTH maintains extracellular calcium and phosphate homeostasis by increasing serum calcium and decreasing serum phosphate.

Half-life60 h
Mostly cleared after≈ 13 daysfive half-lives — our arithmetic

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-12

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

United StatesNo exact match for this strength and form

CanadaNo exact match for this strength and form

NetherlandsNo exact match for this strength and form

Details

Made byAscendis Pharma Bone Diseases A/S
Active substancePalopegteriparatide
Used inHormones, such as thyroid and steroids
ClassificationH05AA · Hormones, such as thyroid and steroids
Orphan medicineYes — designated for a rare disease, according to the register
Additional monitoring ▼Yes — under additional monitoring (black triangle). Report suspected side effects.
Authorised on2023-11-17
Last updated by the regulator2025-06-20
EMA product numberEMEA/H/C/005934

Source: European Medicines Agency — medicine data · 2026-09-30 · not reviewed by a clinician

Source: European Medicines Agency (EMA). Product information as published by EMA. Reuse terms: EMA legal notice (reproduction authorised).