Medicine guide

Zegalogue

  • Prescription status not stated
  • Hormones, such as thyroid and steroids
Active substance
Dasiglucagon
Made by
Zealand Pharma A/S

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

  • Zegalogue is indicated for the treatment of severe hypoglycaemia in adults, adolescents, and children aged 6 years and over with diabetes mellitus.

From the official label · 2026-09-30 · European Medicines Agency

How it works

From the US prescribing label for the same active substance (Zegalogue). It describes the substance, not this exact product.

Dasiglucagon is a glucagon receptor agonist, which increases blood glucose concentration by activating hepatic glucagon receptors, thereby stimulating glycogen breakdown and release of glucose from the liver.

Hepatic stores of glycogen are necessary for dasiglucagon to produce an antihypoglycemic effect.

Peak level after35 min
Half-life30 min
Mostly cleared after≈ 2.5 hfive half-lives — our arithmetic
PeakHalf gone2.5 h0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

Metabolism data indicated that dasiglucagon is cleared like native glucagon through proteolytic degradation pathways in blood, liver, and kidney.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2023-01-01

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

United StatesNo exact match for this strength and form

NetherlandsNo exact match for this strength and form

Details

Made byZealand Pharma A/S
Active substanceDasiglucagon
Used inHormones, such as thyroid and steroids
ClassificationH04AA02 · Hormones, such as thyroid and steroids
Additional monitoring ▼Yes — under additional monitoring (black triangle). Report suspected side effects.
Authorised on2024-07-24
Last updated by the regulator2026-07-03
EMA product numberEMEA/H/C/006214

Source: European Medicines Agency — medicine data · 2026-09-30 · not reviewed by a clinician

Source: European Medicines Agency (EMA). Product information as published by EMA. Reuse terms: EMA legal notice (reproduction authorised).