PROSTINE VR
As listed in the register: PROSTINE VR 0,5 mg/ml, solution injectable
0,5 mg · solution injectable
- Prescription only
- Active substance
- Alprostadil
- Made by
- PFIZER HOLDING FRANCE
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Caverject). It describes the substance, not this exact product.
Alprostadil (PGE1) is a prostaglandin with a wide variety of pharmacological actions including vasodilation and inhibition of platelet aggregation.
Alprostadil induces erection by relaxation of trabecular smooth muscle and by dilation of cavernosal arteries by binding to its receptors and increasing intracellular cyclic adenosine monophosphate (cAMP) levels via modulation of adenylate cyclase.
Alprostadil is converted to compounds which are further metabolized prior to excretion.
The metabolites of alprostadil are excreted primarily by the kidney, with almost 90% of an administered intravenous dose excreted in urine within 24 hours post-dose.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2024-05-13
Safety of the active substance
From the US prescribing label for the same active substance (Caverject). It describes the substance, not this exact product.
- Men who have known hypersensitivity to the drug ( 4 )..
- Men who have conditions that predispose them to priapism, such as sickle cell anemia or sickle cell trait, multiple myeloma, or leukemia ( 4 )..
- Treatment of erectile dysfunction in men with fibrotic conditions of the penis, such as anatomical deformation, angulation, cavernosal fibrosis, or Peyronie's disease ( 4 )..
- Men with penile implants ( 4 ).
The most common (≥10%) adverse reaction is penile pain ( 6.1 ).
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
SpainNo exact match for this strength and form
CanadaNo exact match for this strength and form
NetherlandsNo exact match for this strength and form
Details
| Made by | PFIZER HOLDING FRANCE |
|---|---|
| Active substance | Alprostadil |
| Strength | 0,5 mg |
| Form | solution injectable |
| Route | intraveineuse |
| Dispensing (as stated by the register) | réservé à l'usage HOSPITALIER · prescription réservée aux spécialistes et services REANIMATION MEDICALE · prescription réservée aux spécialistes et services CHIRURGIE NEONATALE · liste I |
| Marketed | Yes, according to the register |
| Authorisation procedure | Procédure nationale |
| Name in the register | PROSTINE VR 0,5 mg/ml, solution injectable |
| Packs | 1 ampoule(s) en verre |
| CIS | 68103252 |
| CIP13 | 3400955415510 |
Source: Base de données publique des médicaments · 2026-09-30 · not reviewed by a clinician
Source : Base de données publique des médicaments (ANSM / Ministère de la Santé), sous Licence Ouverte. Reuse terms: Licence Ouverte / Open Licence (Etalab).
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.