Medicine guide

TAREG

As listed in the register: TAREG 40 mg, comprimé pelliculé sécable

40 mg · comprimé pelliculé sécable

  • Prescription only
Active substance
Valsartan
Made by
NOVARTIS PHARMA

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (valsartan). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Angiotensin II is formed from angiotensin I in a reaction catalyzed by angiotensin-converting enzyme (ACE, kininase II).

Angiotensin II is the principal pressor agent of the renin-angiotensin system, with effects that include vasoconstriction, stimulation of synthesis and release of aldosterone, cardiac stimulation, and renal reabsorption of sodium.

Peak level after2–4 h
Half-life6 h
Mostly cleared after≈ 30 hfive half-lives — our arithmetic
PeakHalf gone30 h0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

In vitro metabolism studies involving recombinant CYP 450 enzymes indicated that the CYP 2C9 isoenzyme is responsible for the formation of valeryl-4-hydroxy valsartan.

With food

Effect of Food With the tablet, food decreases the exposure (as measured by AUC) to valsartan by about 40% and peak plasma concentration (C max ) by about 50%.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-06-25

Safety of the active substance

This product’s leaflet is published as a scanned document. This section quotes the US prescribing label for the same active substance (valsartan). It describes the substance, not this Bulgarian product — its uses and doses can differ.

Serious warning

WARNING: FETAL TOXICITY.

Must not be used by
  • Do not use in patients with known hypersensitivity to any component.
  • Do not coadminister aliskiren with valsartan tablets in patients with diabetes [see Drug Interactions ( 7.3 )].
  • Known hypersensitivity to any component.
Most common side effects

The most common reasons for discontinuation of therapy with valsartan were headache and dizziness.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

Details

Made byNOVARTIS PHARMA
Active substanceValsartan
Strength40 mg
Formcomprimé pelliculé sécable
Routeorale
Dispensing (as stated by the register)liste I
MarketedYes, according to the register
Authorisation procedureProcédure de reconnaissance mutuelle
Name in the registerTAREG 40 mg, comprimé pelliculé sécable
Packsplaquette(s) thermoformée(s) PVC polyéthylène PVDC aluminium de 30 comprimé(s) ( abrogée le 07/10/2024) · plaquette(s) thermoformée(s) PVC polyéthylène PVDC aluminium de 90 comprimé(s) ( abrogée le 07/10/2024) · plaquette(s) PVC PVDC aluminium de 30 comprimé(s) · plaquette(s) PVC PVDC aluminium de 90 comprimé(s)
CIS67813947
CIP133400937138062
CIP133400937138123
CIP133400938154061

Source: Base de données publique des médicaments · 2026-09-30 · not reviewed by a clinician

Source : Base de données publique des médicaments (ANSM / Ministère de la Santé), sous Licence Ouverte. Reuse terms: Licence Ouverte / Open Licence (Etalab).

Other strengths and forms

4 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

  • comprimé pelliculé2 products
  • comprimé pelliculé sécable1 products
    • 40 mg
  • solution buvable1 products

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.