Peptide · Dual GIP and GLP-1 receptor agonist

Tirzepatide

A dual GIP and GLP-1 receptor agonist peptide, authorised as a prescription medicine for type 2 diabetes and weight management.

Approved medicineAuthorised by a regulator, available on prescription.

Legal status · US
Approved medicine
Evidence in people
Molecule
Dual GIP and GLP-1 receptor agonist
In sport
Not named on the WADA list
Status checked

Regulatory status · United States

This describes the position in the United States. Rules in France differ; an approved peptide medicine there is in its national register.

An approved prescription medicine. Its authorised products are in the ordinary catalogue, each with its official label.

Authorised products

BrandAuthorised forHow it is givenFirst US approval
MounjaroType 2 diabetesInjection, once a week2022
ZepboundWeight management; obstructive sleep apnoea with obesityInjection, once a week2023

Doses, warnings and who should not use it are on each product’s official label, linked from its page.

Every authorised product in France

What changed, and when

  1. First US approval, as Mounjaro, for type 2 diabetes.

  2. Approved for chronic weight management, as Zepbound.

  3. Zepbound approved for moderate-to-severe obstructive sleep apnoea in adults with obesity.

What to be careful about

Search interest has produced a large grey market. A vial bought online is not the authorised product and its contents are unverified.

Sources

Regulatory positions change. This page states the date it describes, and nothing on it is legal or medical advice.