Ambrisentan Devatis 5 mg filmomhulde tabletten
As listed in the register: Ambrisentan Devatis 5 mg filmomhulde tabletten
5 mg · filmomhulde tablet
- Prescription only
- Heart, blood pressure and circulation
- Active substance
- Ambrisentan
- Made by
- Devatis GmbH
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Ambrisentan). It describes the substance, not this exact product.
Endothelin-1 (ET-1) is a potent autocrine and paracrine peptide.
Two receptor subtypes, ET A and ET B, mediate the effects of ET-1 in the vascular smooth muscle and endothelium.
Drug Interactions In Vitro Studies Studies with human liver tissue indicate that ambrisentan is metabolized by CYP3A, CYP2C19, and uridine 5'-diphosphate glucuronosyltransferases (UGTs) 1A9S, 2B7S, and 1A3S.
Food does not affect its bioavailability.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-09-03
Safety of the active substance
From the US prescribing label for the same active substance (Ambrisentan). It describes the substance, not this exact product.
WARNING: EMBRYO-FETAL TOXICITY Ambrisentan tablets are contraindicat ed for use during pregnancy because it may cause major birth defects if used by pregnant patients, based on studies in animals [see Contraindications (4.1), Warnings and Precautions (5.1), and Use in Specific Populations (8.1)].
- Pregnancy ( 4.1 ) Idiopathic Pulmonary Fibrosis ( 4.2 ) 4.1 Pregnancy Ambrisentan tablets may cause fetal harm when administered to a pregnant female.
- Ambrisentan tablets are contraindicated in females who are pregnant.
- Ambrisentan was consistently shown to have teratogenic effects when administered to animals.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United States13 matching products
European UnionNo exact match for this strength and form
Spain13 matching products
- AMBRISENTAN ACCORD 5 mg · comprimido recubierto con película
- AMBRISENTAN ALEMBIC 5 mg · comprimido recubierto con película
- AMBRISENTAN ARISTO 5 mg · comprimido recubierto con película
- AMBRISENTAN AUROVITAS 5 mg · comprimido recubierto con película
- AMBRISENTAN BLUEFISH 5 mg · comprimido recubierto con película
- AMBRISENTAN CIPLA 5 mg · comprimido recubierto con película
- AMBRISENTAN DR REDDYS 5 mg · comprimido recubierto con película
- AMBRISENTAN KERN PHARMA 5 mg · comprimido recubierto
France6 matching products
Canada5 matching products
SwitzerlandNo exact match for this strength and form
Details
| Made by | Devatis GmbH |
|---|---|
| Active substance | Ambrisentan |
| Used in | Heart, blood pressure and circulation |
| Strength | 5 mg |
| Form | filmomhulde tablet |
| Classification | C02KX02 · Heart, blood pressure and circulation |
| Route | oraal gebruik |
| Dispensing (as stated by the register) | Uitsluitend recept |
| RVG | 123658 |
Source: Geneesmiddeleninformatiebank · 2026-09-30 · not reviewed by a clinician
Bron: College ter Beoordeling van Geneesmiddelen (CBG). De Rijksoverheid is het niet automatisch eens met de inhoud van deze site. Reuse terms: CC0 1.0 (CBG website).
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.