Denbrayce 120 mg oplossing voor injectie
As listed in the register: Denbrayce 120 mg oplossing voor injectie
120 mg · oplossing voor injectie
- Prescription only
- Muscles, joints and bones
- Active substance
- Denosumab
- Used in
- Muscles, joints and bones
- Made by
- Mabxience Research S.L.
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Bilprevda). It describes the substance, not this exact product.
Denosumab products bind to RANKL, a transmembrane or soluble protein essential for the formation, function, and survival of osteoclasts, the cells responsible for bone resorption, thereby modulating calcium release from bone.
Increased osteoclast activity, stimulated by RANKL, is a mediator of bone pathology in solid tumors with osseous metastases.Similarly, giant cell tumors of bone consist of stromal cells expressing RANKL and osteoclast-like giant cells expressing RANK receptor, and signaling through the RANK receptor contributes to osteolysis and tumor growth.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-18
Safety of the active substance
From the US prescribing label for the same active substance (Bilprevda). It describes the substance, not this exact product.
- ( 4.1 ) Known clinically significant hypersensitivity to denosumab products.
- ( 4.2 ) 4.1 Hypocalcemia Pre-existing hypocalcemia must be corrected prior to initiating therapy with Bilprevda [see Warnings and Precautions ( 5.3 )]. 4.2 Hypersensitivity Bilprevda is contraindicated in patients with known clinically significant hypersensitivity to denosumab products [see Warnings and Precautions ( 5.2 ) and Adverse Reactions ( 6.2 )].
Most common adverse reactions (≥ 10%) were diarrhea, nausea, anemia, back pain, thrombocytopenia, peripheral edema, hypocalcemia, upper respiratory tract infection, rash, and headache.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
European UnionNo exact match for this strength and form
Spain13 matching products
- BOMYNTRA 120 mg · solución inyectable2 makers
- XGEVA 120 mg denosumab · solución inyectable2 makers
- BILPREVDA 120 mg · solución inyectable
- ENWYLMA 120 mg · solución inyectable
- JUBEREQ 120 mg · solución inyectable
- OSENVELT 120 mg · solución inyectable
- VEVZUO 120 mg · solución inyectable
- WYOST 120 mg · solución inyectable
CanadaNo exact match for this strength and form
SwitzerlandNo exact match for this strength and form
Details
| Made by | Mabxience Research S.L. |
|---|---|
| Active substance | Denosumab |
| Used in | Muscles, joints and bones |
| Strength | 120 mg |
| Form | oplossing voor injectie |
| Classification | M05BX04 · Muscles, joints and bones |
| Route | subcutaan gebruik |
| Dispensing (as stated by the register) | Uitsluitend recept |
| RVG | EU/1/25/1936 |
Source: Geneesmiddeleninformatiebank · 2026-09-30 · not reviewed by a clinician
Bron: College ter Beoordeling van Geneesmiddelen (CBG). De Rijksoverheid is het niet automatisch eens met de inhoud van deze site. Reuse terms: CC0 1.0 (CBG website).
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.