Nifedipine retard CF 20 mg
As listed in the register: Nifedipine retard CF 20 mg, tabletten
20 mg · tablet met gereguleerde afgifte
- Prescription only
- Heart, blood pressure and circulation
- Active substance
- Nifedipine
- Made by
- Centrafarm B.V.
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Nifedipine). It describes the substance, not this exact product.
This property increases myocardial oxygen delivery in patients with coronary artery spasm, and is responsible for the effectiveness of nifedipine in vasospastic (Prinzmetal's or variant) angina.
Whether this effect plays any role in classical angina is not clear, but studies of exercise tolerance have not shown an increase in the maximum exercise rate-pressure product, a widely accepted measure of oxygen utilization.
Nifedipine is extensively metabolized to highly water-soluble, inactive metabolites, accounting for 60 to 80% of the dose excreted in the urine.
Administration of the nifedipine extended-release tablets in the presence of food slightly alters the early rate of drug absorption, but does not influence the extent of drug bioavailability.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-04
Safety of the active substance
From the US prescribing label for the same active substance (Nifedipine). It describes the substance, not this exact product.
- Known hypersensitivity reaction to nifedipine.
The most common side effect reported with nifedipine extended-release tablets was edema which was dose related and ranged in frequency from approximately 10% to about 30% at the highest dose studied (180 mg).
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
Spain2 matching products
Canada1 matching products
SwitzerlandNo exact match for this strength and form
Details
| Made by | Centrafarm B.V. |
|---|---|
| Active substance | Nifedipine |
| Used in | Heart, blood pressure and circulation |
| Strength | 20 mg |
| Form | tablet met gereguleerde afgifte |
| Classification | C08CA05 · Heart, blood pressure and circulation |
| Route | oraal gebruik |
| Dispensing (as stated by the register) | Uitsluitend recept |
| Name in the register | Nifedipine retard CF 20 mg, tabletten |
| RVG | 15976 |
Source: Geneesmiddeleninformatiebank · 2026-09-30 · not reviewed by a clinician
Bron: College ter Beoordeling van Geneesmiddelen (CBG). De Rijksoverheid is het niet automatisch eens met de inhoud van deze site. Reuse terms: CC0 1.0 (CBG website).
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.