Salazopyrine zetpil
As listed in the register: Salazopyrine zetpil, zetpillen 500 mg
500 mg · zetpil
- Prescription only
- Digestion, stomach, diabetes and nutrition
- Active substance
- Sulfasalazine
- Made by
- Pfizer B.V.
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Sulfasalazine). It describes the substance, not this exact product.
In ulcerative colitis, clinical studies utilizing rectal administration of SSZ, SP and 5-ASA have indicated that the major therapeutic action may reside in the 5-ASA moiety.
The relative contribution of the parent drug and the major metabolites in rheumatoid arthritis is unknown.
In the intestine, SSZ is metabolized by intestinal bacteria to SP and 5-ASA.
Absorbed SP and 5-ASA and their metabolites are primarily eliminated in the urine either as free metabolites or as glucuronide conjugates.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-25
Safety of the active substance
From the US prescribing label for the same active substance (Sulfasalazine). It describes the substance, not this exact product.
- Sulfasalazine delayed release tablets are contraindicated in: Hypersensitivity to sulfasalazine, its metabolites, sulfonamides or salicylates, Patients with intestinal or urinary obstruction, Patients with porphyria, as the sulfonamides have been reported to precipitate an acute attack.
The most common adverse reactions associated with sulfasalazine in ulcerative colitis are anorexia, headache, nausea, vomiting, gastric distress, and apparently reversible oligospermia.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
SpainNo exact match for this strength and form
FranceNo exact match for this strength and form
CanadaNo exact match for this strength and form
SwitzerlandNo exact match for this strength and form
Details
| Made by | Pfizer B.V. |
|---|---|
| Active substance | Sulfasalazine |
| Used in | Digestion, stomach, diabetes and nutrition |
| Strength | 500 mg |
| Form | zetpil |
| Classification | A07EC01 · Digestion, stomach, diabetes and nutrition |
| Route | rectaal gebruik |
| Dispensing (as stated by the register) | Uitsluitend recept |
| Name in the register | Salazopyrine zetpil, zetpillen 500 mg |
| RVG | 00633 |
Source: Geneesmiddeleninformatiebank · 2026-09-30 · not reviewed by a clinician
Bron: College ter Beoordeling van Geneesmiddelen (CBG). De Rijksoverheid is het niet automatisch eens met de inhoud van deze site. Reuse terms: CC0 1.0 (CBG website).
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.