Teriflunomide Sandoz 14 mg
As listed in the register: Teriflunomide Sandoz 14 mg, filmomhulde tabletten
14 mg · filmomhulde tablet
- Prescription only
- Cancer treatments and immune-system medicines
- Active substance
- Teriflunomide
- Made by
- Sandoz B.V.
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Teriflunomide). It describes the substance, not this exact product.
Teriflunomide, an immunomodulatory agent with anti-inflammatory properties, inhibits dihydroorotate dehydrogenase, a mitochondrial enzyme involved in de novo pyrimidine synthesis.
The exact mechanism by which teriflunomide exerts its therapeutic effect in multiple sclerosis is unknown but may involve a reduction in the number of activated lymphocytes in CNS.
Drug Interaction Studies Teriflunomide is not metabolized by Cytochrome P450 or flavin monoamine oxidase enzymes.
Teriflunomide is eliminated mainly through direct biliary excretion of unchanged drug as well as renal excretion of metabolites.
Food does not have a clinically relevant effect on teriflunomide pharmacokinetics.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-26
Safety of the active substance
From the US prescribing label for the same active substance (Teriflunomide). It describes the substance, not this exact product.
WARNING: HEPATOTOXICITY and EMBRYOFETAL TOXICITY Hepatotoxicity Clinically significant and potentially life-threatening liver injury, including acute liver failure requiring transplant, has been reported in patients treated with teriflunomide in the postmarketing setting [see Warnings and Precautions ( 5.1 )].
- Teriflunomide is contraindicated in/with: Patients with severe hepatic impairment [see Warnings and Precautions ( 5.1 )].
- Pregnant women and females of reproductive potential not using effective contraception.
- Teriflunomide may cause fetal harm [see Warnings and Precautions ( 5.2, 5.3 ) and Use in Specific Populations ( 8.1 )].
- Patients with a history of a hypersensitivity reaction to teriflunomide, leflunomide, or to any of the inactive ingredients in teriflunomide tablets.
The most common were headache, an increase in ALT, diarrhea, alopecia, and nausea.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United States15 matching products
European UnionNo exact match for this strength and form
Spain22 matching products
- AUBAGIO 14 mg · comprimido recubierto con película2 makers
- CLEFIREM 14 mg · comprimido recubierto con película
- TERIFLUNOMIDA ACCORD 14 MG · comprimido recubierto con película
- TERIFLUNOMIDA AUROVITAS 14 mg · comprimido recubierto con película
- TERIFLUNOMIDA DESITIN 14 mg · comprimido recubierto con película
- TERIFLUNOMIDA DR REDDYS 14 mg · comprimido recubierto con película
- TERIFLUNOMIDA GLENMARK 14 mg · comprimido recubierto con película
- TERIFLUNOMIDA KERN PHARMA 14 mg · comprimido recubierto con película
Canada8 matching products
SwitzerlandNo exact match for this strength and form
Details
| Made by | Sandoz B.V. |
|---|---|
| Active substance | Teriflunomide |
| Used in | Cancer treatments and immune-system medicines |
| Strength | 14 mg |
| Form | filmomhulde tablet |
| Classification | L04AK02 · Cancer treatments and immune-system medicines |
| Route | oraal gebruik |
| Dispensing (as stated by the register) | Uitsluitend recept |
| Name in the register | Teriflunomide Sandoz 14 mg, filmomhulde tabletten |
| RVG | 128862 |
Source: Geneesmiddeleninformatiebank · 2026-09-30 · not reviewed by a clinician
Bron: College ter Beoordeling van Geneesmiddelen (CBG). De Rijksoverheid is het niet automatisch eens met de inhoud van deze site. Reuse terms: CC0 1.0 (CBG website).
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.