Medicine guide

Trental 400 mg

As listed in the register: Trental 400 mg, tabletten met gereguleerde afgifte

400 mg · tablet met gereguleerde afgifte

  • Prescription only
  • Heart, blood pressure and circulation
Active substance
Pentoxifylline
Made by
Euro Registratie Collectief B.V.

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupHeart, blood pressure and circulationC04AD03

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

From the US prescribing label for the same active substance (Pentoxifylline). It describes the substance, not this exact product.

Mode of Action: Pentoxifylline and its metabolites improve the flow properties of blood by decreasing its viscosity.

In patients with chronic peripheral arterial disease, this increases blood flow to the affected microcirculation and enhances tissue oxygenation.

Peak level after1 h
With food

Food intake shortly before dosing delays absorption of an immediate-release dosage form but does not affect total absorption.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-05-15

Safety of the active substance

From the US prescribing label for the same active substance (Pentoxifylline). It describes the substance, not this exact product.

Must not be used by
  • Pentoxifylline extended-release tablets should not be used in patients with recent cerebral and/or retinal hemorrhage or in patients who have previously exhibited intolerance to this product or methylxanthines such as caffeine, theophylline, and theobromine.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

Details

Made byEuro Registratie Collectief B.V.
Active substancePentoxifylline
Used inHeart, blood pressure and circulation
Strength400 mg
Formtablet met gereguleerde afgifte
ClassificationC04AD03 · Heart, blood pressure and circulation
Routeoraal gebruik
Dispensing (as stated by the register)Uitsluitend recept
Name in the registerTrental 400 mg, tabletten met gereguleerde afgifte
RVG113167//11175

Source: Geneesmiddeleninformatiebank · 2026-09-30 · not reviewed by a clinician

Bron: College ter Beoordeling van Geneesmiddelen (CBG). De Rijksoverheid is het niet automatisch eens met de inhoud van deze site. Reuse terms: CC0 1.0 (CBG website).

Other strengths and forms

2 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

  • tablet met gereguleerde afgifte2 products

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.