Voxzogo 1
As listed in the register: Voxzogo 1,2 mg, poeder en oplosmiddel voor oplossing voor injectie
1,2 mg · poeder voor oplossing voor injectie
- Prescription only
- Muscles, joints and bones
- Active substance
- Vosoritide
- Used in
- Muscles, joints and bones
- Made by
- BioMarin International Limited
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (VOXZOGO 0.4mg). It describes the substance, not this exact product.
In patients with achondroplasia, endochondral bone growth is negatively regulated due to a gain of function mutation in fibroblast growth factor receptor 3 ( FGFR3 ).
Binding of vosoritide to natriuretic peptide receptor-B (NPR-B) antagonizes FGFR3 downstream signaling by inhibiting the extracellular signal-regulated kinases 1 and 2 (ERK1/2) in the mitogen-activated protein kinase (MAPK) pathway at the level of rapidly accelerating fibrosarcoma serine/threonine protein kinase (RAF-1).
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-11-25
Safety of the active substance
From the US prescribing label for the same active substance (VOXZOGO 0.4mg). It describes the substance, not this exact product.
Most common adverse reactions (>10%) are injection site erythema, injection site swelling, rash, vomiting, injection site urticaria, arthralgia, decreased blood pressure, and gastroenteritis.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
United StatesNo exact match for this strength and form
European UnionNo exact match for this strength and form
Spain1 matching products
France1 matching products
CanadaNo exact match for this strength and form
SwitzerlandNo exact match for this strength and form
Details
| Made by | BioMarin International Limited |
|---|---|
| Active substance | Vosoritide |
| Used in | Muscles, joints and bones |
| Strength | 1,2 mg |
| Form | poeder voor oplossing voor injectie |
| Classification | M05BX07 · Muscles, joints and bones |
| Route | subcutaan gebruik |
| Dispensing (as stated by the register) | Uitsluitend recept |
| Name in the register | Voxzogo 1,2 mg, poeder en oplosmiddel voor oplossing voor injectie |
| RVG | EU/1/21/1577 |
Source: Geneesmiddeleninformatiebank · 2026-09-30 · not reviewed by a clinician
Bron: College ter Beoordeling van Geneesmiddelen (CBG). De Rijksoverheid is het niet automatisch eens met de inhoud van deze site. Reuse terms: CC0 1.0 (CBG website).
Other strengths and forms
2 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- poeder voor oplossing voor injectie2 products
- 1,2 mg
- 1,4 mg
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.