Active substance

Acetaminophen, Diphenhydramine Hydrochloride, Phenylephrine Hydrochloride

5 products from 4 companies contain this in United States.

5 without prescriptionPowder, for SolutionSolutionPowder

Available without a prescription

Basic Care Severe Cold and Cough650 mg + 25 mg + 10 mgWithout prescriptionPowder, for Solution Amazon.com Services LLC · Acetaminophen, Diphenhydramine Hydrochloride, Phenylephrine Hydrochloride Dg Health Flu and Severe Cold and Cough650 mg + 25 mg + 10 mgWithout prescriptionPowder, for Solution Dolgencorp, LLC · Acetaminophen, Diphenhydramine Hydrochloride, Phenylephrine Hydrochloride Equate Flu and Severe Cold and Cough650 mg + 25 mg + 10 mgWithout prescriptionPowder, for Solution Wal-Mart Stores Inc · Acetaminophen, Diphenhydramine Hydrochloride, Phenylephrine Hydrochloride Robitussin Severe Multi-Symptom Cough Cold Flu Nighttime650 mg/20mL + 25 mg/20mL + 10 mg/20mLWithout prescriptionSolution Haleon US Holdings LLC · Acetaminophen, Diphenhydramine Hydrochloride, Phenylephrine Hydrochloride Theraflu Severe Cold Relief Nighttime500 mg + 25 mg + 10 mgWithout prescriptionPowder Haleon US Holdings LLC · Acetaminophen, Diphenhydramine Hydrochloride, Phenylephrine Hydrochloride

Same substance is not the same product. Strength, form, release mechanism and other ingredients all differ. Whether one can replace another is a decision for a pharmacist.