Active substance

Naproxen Sodium, Pseudoephedrine Hydrochloride

3 products from 3 companies contain this in United States.

3 without prescriptionTabletTablet, Extended ReleaseTablet, Film Coated, Extended Release

Available without a prescription

Aleve-D Sinus and Headache220 mg + 120 mgWithout prescriptionTablet Bayer HealthCare LLC. · Naproxen Sodium, Pseudoephedrine Hydrochloride Mucinex Ds 12hr Cold, Fever and Sinus220 mg + 120 mgWithout prescriptionTablet, Extended Release Reckitt Benckiser LLC · Naproxen Sodium, Pseudoephedrine Hydrochloride Sinus and Cold D220 mg + 120 mgWithout prescriptionTablet, Film Coated, Extended Release CVS WOONSOCKET PRESCRIPTION CENTER, INCORPORATED · Naproxen Sodium, Pseudoephedrine Hydrochloride

Same substance is not the same product. Strength, form, release mechanism and other ingredients all differ. Whether one can replace another is a decision for a pharmacist.