Medicine guide

Alka-Seltzer Plus Severe Cold Night Powerfast Fizz

325 mg + 2 mg + 10 mg + 7.8 mg · Tablet, Effervescent

Active substance: Aspirin, Chlorpheniramine Maleate, Dextromethorphan Hydrobromide, Phenylephrine Bitartrate
Used in: Blood, clotting and anaemia
Made by: Bayer HealthCare LLC.
Source: Official label

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupBlood, clotting and anaemia

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

Made by	Bayer HealthCare LLC.
Active substance	Aspirin, Chlorpheniramine Maleate, Dextromethorphan Hydrobromide, Phenylephrine Bitartrate
Used in	Blood, clotting and anaemia
Strength	325 mg + 2 mg + 10 mg + 7.8 mg
Form	Tablet, Effervescent
Route	Oral
Packs	12 POUCH in 1 CARTON / 2 TABLET, EFFERVESCENT in 1 POUCH · 10 POUCH in 1 CARTON / 2 TABLET, EFFERVESCENT in 1 POUCH
NDC	0280-0121

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

2 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Tablet, Effervescent2 products
- 325 mg + 2 mg + 10 mg + 7.8 mg
- 325 mg + 6.25 mg + 10 mg + 7.8 mg

These contain the same substance. That does not mean one can replace another — ask a pharmacist.