Mediclarum
Medicine guide

Alprazolam

.25 mg · Tablet

  • Prescription only
  • Controlled substance · CIV
  • Benzodiazepine
Active substance
Alprazolam
Made by
Bryant Ranch Prepack

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupPain, sleep, mood, epilepsy and the brain

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

From the US prescribing label for the same active substance (Alprazolam). It describes the substance, not this exact product.

Alprazolam is a 1,4 benzodiazepine.

Alprazolam exerts its effect for the acute treatment of generalized anxiety disorder and panic disorder through binding to the benzodiazepine site of gamma-aminobutyric acid-A (GABA A ) receptors in the brain and enhances GABA-mediated synaptic inhibition.

Peak level after1–2 h
Half-life11.2 h
Mostly cleared after≈ 2 daysfive half-lives — our arithmetic
PeakHalf gone2 days0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

Alprazolam is extensively metabolized in humans, primarily by cytochrome P450 3A4 (CYP3A4), to 2 major active metabolites in the plasma: 4-hydroxyalprazolam and α-hydroxyalprazolam.

How it leaves the body

Alprazolam and its metabolites are excreted primarily in the urine.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-07-28

Safety of the active substance

From the US prescribing label for the same active substance (Alprazolam). It describes the substance, not this exact product.

Serious warning

WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death.

Must not be used by
  • Alprazolam tablets are contraindicated in patients: with known hypersensitivity to alprazolam or other benzodiazepines.
  • Angioedema has been reported [see Adverse Reactions (6.2) ]. taking strong cytochrome P450 3A (CYP3A) inhibitors (e.g., ketoconazole, itraconazole), except ritonavir [see Dosage and Administration (2.6), Warnings and Precautions (5.5), Drug Interactions (7.1) ] Known hypersensitivity to alprazolam or other benzodiazepines.
  • ( 4 ) Concomitant use with strong cytochrome P450 3A (CYP3A) inhibitors, except ritonavir.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

Bulgaria3 matching products

Every strength and form (52)

Spain21 matching products

Every strength and form (85)

France14 matching products

Every strength and form (28)

Canada5 matching products

Every strength and form (18)

Netherlands6 matching products

Every strength and form (23)

Details

Made byBryant Ranch Prepack
Active substanceAlprazolam
Used inPain, sleep, mood, epilepsy and the brain
Strength.25 mg
FormTablet
RouteOral
Packs10 TABLET in 1 BOTTLE · 30 TABLET in 1 BOTTLE
NDC71335-2133
NDC71335-9667

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

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Other strengths and forms

104 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.

Alprazolam1 mg/mLPrescription onlySolution, Concentrate Hikma Pharmaceuticals USA Inc. · AlprazolamAlprazolam.25 mgPrescription onlyTablet Actavis Pharma, Inc. · AlprazolamAlprazolam.5 mgPrescription onlyTablet Actavis Pharma, Inc. · AlprazolamAlprazolam1 mgPrescription onlyTablet Actavis Pharma, Inc. · AlprazolamAlprazolam2 mgPrescription onlyTablet Actavis Pharma, Inc. · AlprazolamAlprazolam.25 mgPrescription onlyTablet, Orally Disintegrating Actavis Pharma, Inc. · Alprazolam

See every product with Alprazolam