Ativan
2 mg/mL · Injection
- Prescription only
- Controlled substance · CIV
- Benzodiazepine
- Active substance
- Lorazepam
- Made by
- Hikma Pharmaceuticals USA Inc.
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
This information is not included in the verified source. Open the official leaflet
How it works
From the US prescribing label for the same active substance (LOREEV XR). It describes the substance, not this exact product.
Lorazepam exerts its effect for the treatment of anxiety disorders through binding to the benzodiazepine site of the gamma-aminobutyric acid-A (GABA A ) receptors in the brain and enhances GABA-mediated synaptic inhibition.
Lorazepam glucuronide is excreted in the urine.
Effect of Food Administration of LOREEV XR with a high-fat and high calorie meal did not have a significant effect on exposure of LOREEV XR.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-10-08
Safety of the active substance
From the US prescribing label for the same active substance (LOREEV XR). It describes the substance, not this exact product.
WARNING: RISKS FROM CONCOMITANT USE WITH OPIOIDS; ABUSE, MISUSE, AND ADDICTION; and DEPENDENCE AND WITHDRAWAL REACTIONS Concomitant use of benzodiazepines and opioids may result in profound sedation, respiratory depression, coma, and death.
- LOREEV XR is contraindicated in patients with: hypersensitivity to benzodiazepines or to any of the ingredients in LOREEV XR [see Warnings and Precautions ( 5.7 )]. acute narrow-angle glaucoma Hypersensitivity to benzodiazepines or any ingredients in LOREEV XR ( 4 ) Acute narrow-angle glaucoma ( 4 )
The most frequent adverse reactions to lorazepam tablets were sedation (15.9%), dizziness (6.9%), weakness (4.2%), and unsteadiness (3.4%).
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
SpainNo exact match for this strength and form
CanadaNo exact match for this strength and form
Details
| Made by | Hikma Pharmaceuticals USA Inc. |
|---|---|
| Active substance | Lorazepam |
| Used in | Pain, sleep, mood, epilepsy and the brain |
| Strength | 2 mg/mL |
| Form | Injection |
| Route | Intramuscular; Intravenous |
| Packs | 10 VIAL in 1 CARTON / 10 mL in 1 VIAL · 25 VIAL in 1 CARTON / 1 mL in 1 VIAL |
| NDC | 0641-6000 |
| NDC | 0641-6001 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
5 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.