Buspirone Hydrochloride
5 mg · Tablet
- Prescription only
- Active substance
- Buspirone Hydrochloride
- Made by
- Zydus Lifesciences Limited
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
This information is not included in the verified source. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Buspirone Hydrochloride). It describes the substance, not this exact product.
The mechanism of action of buspirone is unknown.
Buspirone differs from typical benzodiazepine anxiolytics in that it does not exert anticonvulsant or muscle relaxant effects.
Buspirone is metabolized primarily by oxidation, which in vitro has been shown to be mediated by cytochrome P450 3A4 (CYP3A4) (see PRECAUTIONS, Drug Interactions ).
In a single-dose study using 14 C-labeled buspirone, 29% to 63% of the dose was excreted in the urine within 24 hours, primarily as metabolites; fecal excretion accounted for 18% to 38% of the dose.
The effects of food upon the bioavailability of buspirone hydrochloride tablets have been studied in eight subjects.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2024-05-15
Safety of the active substance
From the US prescribing label for the same active substance (Buspirone Hydrochloride). It describes the substance, not this exact product.
- Buspirone hydrochloride tablets are contraindicated in patients hypersensitive to buspirone hydrochloride.
- The use of monoamine oxidase inhibitors (MAOIs) intended to treat depression with buspirone or within 14 days of stopping treatment with buspirone is contraindicated because of an increased risk of serotonin syndrome and/or elevated blood pressure.
- The use of buspirone within 14 days of stopping an MAOI intended to treat depression is also contraindicated.
- Starting buspirone in a patient who is being treated with reversible MAOIs such as linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome (see WARNINGS, DOSAGE AND ADMINISTRATION and DRUG INTERACTIONS ).
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
Canada2 matching products
Details
| Made by | Zydus Lifesciences Limited |
|---|---|
| Active substance | Buspirone Hydrochloride |
| Strength | 5 mg |
| Form | Tablet |
| Route | Oral |
| Packs | 100 TABLET in 1 BOTTLE · 500 TABLET in 1 BOTTLE |
| NDC | 65841-781 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
168 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.