Corlanor
7.5 mg · Tablet, Film Coated
- Prescription only
- Hyperpolarization-activated Cyclic Nucleotide-gated Channel Blocker
- Active substance
- Ivabradine
- Made by
- Amgen Inc
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Ivabradine). It describes the substance, not this exact product.
Ivabradine blocks the hyperpolarization-activated cyclic nucleotide-gated (HCN) channel responsible for the cardiac pacemaker I f current, which regulates heart rate.
In clinical electrophysiology studies, the cardiac effects were most pronounced in the sinoatrial (SA) node, but prolongation of the AH interval has occurred as has PR interval prolongation.
Ivabradine is extensively metabolized in the liver and intestines by CYP3A4-mediated oxidation.
The total clearance of ivabradine is 24 L/h, and renal clearance is approximately 4.2 L/h, with ~ 4% of an oral dose excreted unchanged in urine.
Food delays absorption by approximately 1 hour and increases plasma exposure by 20% to 40%.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-04-24
Safety of the active substance
From the US prescribing label for the same active substance (Ivabradine). It describes the substance, not this exact product.
- Ivabradine is contraindicated in patients with:.
- Acute decompensated heart failure.
- Clinically significant hypotension.
- Sick sinus syndrome, sinoatrial block or 3 rd degree AV block, unless a functioning demand pacemaker is present.
Most common adverse reactions occurring in ≥ 1% of patients are bradycardia, hypertension, atrial fibrillation and luminous phenomena (phosphenes).
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
Bulgaria9 matching products
- Inevica 7,5 mg · film - coated tablets2 makers
- APREDONAV 7,5 mg · film - coated tablets
- Bixebra 7,5 mg · film - coated tablets
- Corledin 7,5 mg · film-coated tablets
- Ivabenor 7,5 mg · film-coated tablets
- Ivabradine Viatris 7,5 mg · film - coated tablets
- Normobradine 7,5 mg · film - coated tablets
- Raenom 7,5 mg · film - coated tablets
European UnionNo exact match for this strength and form
Details
| Made by | Amgen Inc |
|---|---|
| Active substance | Ivabradine |
| Strength | 7.5 mg |
| Form | Tablet, Film Coated |
| Route | Oral |
| Packs | 60 TABLET, FILM COATED in 1 BOTTLE |
| NDC | 55513-810 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
3 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.