Dermacinrx Clorhexacin
Kit
- Prescription only
- Active substance
- Mupirocin Ointment
- Made by
- PureTek Corporation
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
At a glance
Quoted from the official label · 2024-12-13
Antiseptic · Skin Protectant
- S. aureus and S. pyogenes .
Wet hands with water dispense about 5 ml of product into cupped hands and wash in a vigorous manner for 15 seconds rinse and dry thoroughly Patient preoperative skin preparation:
Full directions ↓This drug is contraindicated in individuals with a history of sensitivity reactions to any of its components.
All warnings ↓- Prescription only
- FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02
Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed
What it is for
Mupirocin Ointment USP, 2% is indicated for the topical treatment of impetigo due to:
- S. aureus and S. pyogenes .
- surgical hand scrub:
- significantly reduces the number of microorganisms on the hands and forearms prior to surgery or patient care healthcare personnel handwash:
- helps reduce bacteria that potentially can cause disease patient preoperative skin preparation:
- for the preparation of the patient's skin prior to surgeryskin wound and general skin cleansing skin wound and general skin cleansing
- for the treatment and/or prevention of diaper rash temporarily protects and helps relieve chapped or cracked skin
From the official label · 2024-12-13 · DailyMed
How it works
From this product’s own US prescribing label.
Application of 14 C-labeled mupirocin ointment to the lower arm of normal male subjects followed by occlusion for 24 hours showed no measurable systemic absorption (<1.1 nanogram mupirocin per milliliter of whole blood).
Measurable radioactivity was present in the stratum corneum of these subjects 72 hours after application.
Following intravenous or oral administration, mupirocin is rapidly metabolized.
The principal metabolite, monic acid, is eliminated by renal excretion, and demonstrates no antibacterial activity.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2024-12-13
Do not take it if
This drug is contraindicated in individuals with a history of sensitivity reactions to any of its components.
Quoted from the official label, section “Contraindications”.
How to take it
These directions are for this exact strength and form. Another one is different.
- A small amount of Mupirocin Ointment USP, 2% should be applied to the affected area 3 times daily. The area treated may be covered with a gauze dressing if desired. Patients not showing a clinical response within 3 to 5 days should be re-evaluated.
- use with care in premature infants and infants under 2 months of age.
- These products may cause irritation or chemical burns.
- Surgical hand scrub:
- wet hands and forearms with water scrub for 3 minutes with about 5 ml of product and a wet brush paying close attention to the nails, cuticles and interdigital spaces a separate nail cleaner may be used rinse thoroughly wash for an additional 3 minutes with 5 ml of product and rinse under running water dry thoroughly Healthcare personnel handwash:
- wet hands with water dispense about 5 ml of product into cupped hands and wash in a vigorous manner for 15 seconds rinse and dry thoroughly Patient preoperative skin preparation:
- apply product liberally to surgical site and swab for at least 2 minutes and dry with a sterile towel repeat procedure for an additional 2 minutes and dry with a sterile towel Skin wound and general skin cleaning:
- thoroughly rinse the area to be cleaned with water apply the minimum amount of product necessary to cover the skin or wound area and wash gently rinse again thoroughly
- apply cream liberally as needed
Quoted from the official label, section “Dosage & Administration”.
Other warnings
- Mupirocin Ointment USP, 2% is not for ophthalmic use.
- For external use only.
- Do not use
- if you are allergic to chlorhexidine gluconate or any other ingredients in contact with meninges in the genital area as a preoperative skin preparation of the head or face
- When using this product
- keep out of eyes, ears, and mouth.
- May cause serious and permanent eye injury if placed or kept in the eye during surgical procedures or may cause deafness when instilled in the middle ear through perforated eardrums. if solution should contact these areas, rinse out promptly and thoroughly with water wounds which involve more than the superficial layers of the skin should not be routinely treated repeated general skin cleansing of large body areas should not be done except when the underlying condition makes it necessary to reduce the bacterial population of skin
- Stop use and
- ask a doctor if irritation, sensitization or allergic reaction occurs.
- These may be signs of a serious condition.
- Keep out of reach of children if swallowed, get medical help or contact a Poison Control Center right away.
- For external use only
- Do not use on deep or puncture wounds animal bites serious burns
- When using this product do not get into eyes
- Stop use and
- ask a doctor if condition worsens symptoms last more than 7 days or clear up and occur again within a few days
- Keep out of reach of children.
- If swallowed, get medical help or contact a Poison Control Center right away.
- If a reaction suggesting sensitivity or chemical irritation should occur with the use of Mupirocin Ointment USP, 2%, treatment should be discontinued and appropriate alternative therapy for the infection instituted.
- As with other antibacterial products, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi.
- Mupirocin Ointment USP, 2% is not formulated for use on mucosal surfaces.
- Intranasal use has been associated with isolated reports of stinging and drying.
- A paraffin-based formulation - *Bactroban Nasal ® (mupirocin calcium ointment) – is available for intranasal use.
- Polyethylene glycol can be absorbed from open wounds and damaged skin and is excreted by the kidneys.
- In common with other polyethylene glycol-based ointments, Mupirocin Ointment USP, 2% should not be used in conditions where absorption of large quantities of polyethylene glycol is possible, especially if there is evidence of moderate or severe renal impairment.
- Information for Patients - Use this medication only as directed by your healthcare provider.
- It is for external use only.
- Avoid contact with the eyes.
- The medication should be stopped and your healthcare practitioner contacted if irritation, severe itching, or rash occurs.
- If impetigo has not improved in 3 to 5 days, contact your healthcare practitioner.
- Drug Interactions - The effect of the concurrent application of Mupirocin Ointment USP, 2% and other drug products has not been studied.
- Carcinogenesis, Mutagenesis, Impairment of Fertility - Long-term studies in animals to evaluate carcinogenic potential of mupirocin have not been conducted.
- Results of the following studies performed with mupirocin calcium or mupirocin sodium in vitro and in vivo did not indicate a potential for genotoxicity:
- Rat primary hepatocyte unscheduled DNA synthesis, sediment analysis for DNA strand breaks, Salmonella reversion test (Ames), Escherichia coli mutation assay, metaphase analysis of human lymphocytes, mouse lymphoma assay, and bone marrow micronuclei assay in mice.
- Reproduction studies were performed in male and female rats with mupirocin administered subcutaneously at doses up to 14 times a human topical dose (approximately 60 mg mupirocin per day) on a mg/m 2 basis and revealed no evidence of impaired fertility and reproductive performance from mupirocin.
- Pregnancy:
- Teratogenic Effects - Reproduction studies have been performed in rats and rabbits with mupirocin administered subcutaneously at doses up to 22 and 43 times, respectively, the human topical dose (approximately 60 mg mupirocin per day) on a mg/m 2 basis and revealed no evidence of harm to the fetus due to mupirocin.
- There are however, no adequate and well-controlled studies in pregnant women.
- Because animal studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed.
- Nursing Mothers - It is not known whether this drug is excreted in human milk.
- Because many drugs are excreted in human milk, caution should be exercised when Mupirocin Ointment USP, 2% is administered to a nursing woman.
- Pediatric Use - The safety and effectiveness of Mupirocin Ointment USP, 2% have been established in the age range of 2 months to 16 years.
- Use of mupirocin ointment USP, 2% in these age groups is supported by evidence from adequate and well-controlled studies of mupirocin ointment USP, 2% in impetigo in pediatric patients studied as part of the pivotal clinical trials (see CLINICAL STUDIES ).
Quoted from the official label, section “Warnings”.
Side effects
- The following local adverse reactions have been reported in connection with the use of mupirocin ointment USP, 2%:
- Burning, stinging, or pain in 1.5% of patients; itching in 1% of patients; rash, nausea, erythema, dry skin, tenderness, swelling, contact dermatitis, and increased exudate in less than 1% of patients.
- Systemic reactions to mupirocin ointment USP, 2% have occurred rarely.
Quoted from the official label, section “Adverse Reactions”.
What it looks like and how it is packed
- Mupirocin Ointment USP, 2% is available as follows:
- 22 gram tube (NDC 45802-112-22)
- Store at 20-25°C (68-77°F) [see USP Controlled Room Temperature]. *Bactroban Nasal ® is a registered trademark of GlaxoSmithKline.
Quoted from the official label, section “How Supplied”.
How to store it
- store at 20-25ºC (68-77ºF) avoid excessive heat above 40ºC (104ºF)
- protect from freezing avoid excessive heat
Quoted from the official label, section “Storage and Handling”.
What kind of medicine it is
- Antiseptic
- Skin Protectant
Quoted from the official label, section “OTC — Purpose”.
Other ingredients
Relevant if you react to a dye, a preservative, lactose or gluten.
- cocamide DEA, fragrance, glucono-delta-lactone, hydroxyethylcellulose, isopropyl alcohol, lauramine oxide, PEG-75 lanolin, purified water, tridecyl alcohol.
- Aleurites moluccana seed oil, Aloe barbadensis ( Aloe vera ) leaf juice, butylene glycol, caprylyl glycol, Carthamus tinctorius (safflower) seed oil, cetyl alcohol, chlorphenesin, dimethicone crosspolymer, disodium EDTA, fragrance, glycerin, glyceryl stearate, DermacinRx Complex ® [consisting of:
- bisabolol, calcium pantothenate (vitamin B 5 ), Carthamus tinctorius (safflower) oleosomes, maltodextrin, niacinamide (vitamin B 3 ), pyridoxine HCl (vitamin B 6 ), silica, sodium ascorbyl phosphate (vitamin C), sodium starch octenylsuccinate, tocopheryl acetate (vitamin E), Zingiber officinale (ginger) root extract], PEG-100 stearate, pentaerythrityl tetra-di-t-butyl hydroxyhydrocinnamate, phenoxyethanol, purified water, sodium hyaluronate, stearic acid, triethanolamine.
Quoted from the official label, section “Inactive Ingredients”.
What is in it
- Each gram of Mupirocin Ointment USP, 2% contains 20 mg mupirocin in a bland water miscible ointment base (polyethylene glycol ointment, NF) consisting of polyethylene glycol 400 and polyethylene glycol 3350.
- Mupirocin is a naturally occurring antibiotic.
- The chemical name is ( E )-(2 S ,3 R ,4 R ,5 S )-5-[(2 S ,3 S ,4 S ,5 S )-2,3-Epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-β-methyl-2H-pyran-2-crotonic acid, ester with 9-hydroxynonanoic acid.
- The molecular formula of mupirocin is C 26 H 44 O 9 and the molecular weight is 500.62.
- The chemical structure is: image description
Quoted from the official label, section “Description”.
Ingredients people check for
Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.
- Alcohol (ethanol)
tridecyl alcohol
Matters for children, in pregnancy, in recovery and with some medicines.
Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.
Details
| Made by | PureTek Corporation |
|---|---|
| Active substance | Mupirocin Ointment |
| Form | Kit |
| Packs | 1 KIT in 1 CARTON * 237 mL in 1 BOTTLE, PLASTIC * 118 mL in 1 TUBE * 1 TUBE in 1 CARTON / 22 g in 1 TUBE |
| NDC | 59088-391 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.