Duloxetine Delayed-Release
60 mg · Capsule, Delayed Release Pellets
- Prescription only
- Serotonin and Norepinephrine Reuptake Inhibitor
- Active substance
- Duloxetine Hydrochloride
- Made by
- Proficient Rx LP
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Duloxetine Delayed-Release). It describes the substance, not this exact product.
Although the exact mechanisms of the antidepressant, central pain inhibitory and anxiolytic actions of duloxetine in humans are unknown, these actions are believed to be related to its potentiation of serotonergic and noradrenergic activity in the CNS.
Elimination of duloxetine is mainly through hepatic metabolism involving two P450 isozymes, CYP1A2 and CYP2D6.
Most (about 70%) of the duloxetine dose appears in the urine as metabolites of duloxetine; about 20% is excreted in the feces.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-20
Safety of the active substance
From the US prescribing label for the same active substance (Duloxetine Delayed-Release). It describes the substance, not this exact product.
WARNING: SUICIDAL THOUGHTS AND BEHAVIORS Antidepressants increased the risk of suicidal thoughts and behavior in children, adolescents, and young adults in short-term studies.
- The use of MAOIs intended to treat psychiatric disorders with Duloxetine delayed-release capsules or within 5 days of stopping treatment with Duloxetine delayed-release capsules is contraindicated because of an increased risk of serotonin syndrome.
- The use of Duloxetine delayed-release capsules within 14 days of stopping an MAOI intended to treat psychiatric disorders is contraindicated [see Dosage and Administration (2.8) and Warnings and Precautions (5.4) ].
- Starting Duloxetine delayed-release capsules in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome [see Dosage and Administration (2.9) and Warnings and Precautions (5.4) ].
- Concomitant use of an MAOI antidepressant with Duloxetine delayed-release capsules is contraindicated Use of Duloxetine delayed-release capsules within 14 days of stopping an MAOI antidepressant is contraindicated In linezolid- or intravenous methylene blue-treated patients, initiation of Duloxetine delayed-release capsules is contraindicated ( 4 )
Most Common Adverse Reactions in Adult Trials The most commonly observed adverse reactions in Duloxetine delayed-release capsules-treated patients (as defined above) were: Diabetic Peripheral Neuropathic Pain: nausea, somnolence, decreased appetite, constipation, hyperhidrosis, and dry mouth.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
Bulgaria8 matching products
- Aritavi 60 mg gastro-resistant capsules, hard · gastro-resistant capsule, hard2 makers
- Dulasolan 60 mg gastro-resistant capsules, hard · gastro-resistant capsule, hard
- Dulodet 60 mg · gastro-resistant hard capsule
- Duloxi 60 mg gastro-resistant capsules, hard · gastro-resistant capsule, hard
- Dulsevia 60 mg hard gastro-resistant capsules · gastro-resistant capsule, hard
- Duxet 60 mg gastro-resistant capsules, hard · gastro-resistant capsule, hard
- ONELAR 60 mg hard gastro-resistant capsules · gastro-resistant capsule, hard
European UnionNo exact match for this strength and form
Details
| Made by | Proficient Rx LP |
|---|---|
| Active substance | Duloxetine Hydrochloride |
| Used in | Pain, sleep, mood, epilepsy and the brain |
| Strength | 60 mg |
| Form | Capsule, Delayed Release Pellets |
| Route | Oral |
| Packs | 30 CAPSULE, DELAYED RELEASE PELLETS in 1 BOTTLE · 60 CAPSULE, DELAYED RELEASE PELLETS in 1 BOTTLE |
| NDC | 63187-735 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
25 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Capsule, Delayed Release Pellets25 products
60 mg6
60 mg · 6 companies
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.