Estradiol
.0375 mg/d · Patch, Extended Release
- Prescription only
- Estrogen
- Active substance
- Estradiol
- Made by
- Sandoz Inc
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
This information is not included in the verified source. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Estradiol). It describes the substance, not this exact product.
Endogenous estrogens are largely responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics.
Although circulating estrogens exist in a dynamic equilibrium of metabolic interconversions, estradiol is the principal intracellular human estrogen and is substantially more potent than its metabolites, estrone and estriol at the receptor level.
Exogenous estrogens are metabolized in the same manner as endogenous estrogens.
Estradiol, estrone, and estriol are excreted in the urine along with glucuronide and sulfate conjugates.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-07-21
Safety of the active substance
From the US prescribing label for the same active substance (Estradiol). It describes the substance, not this exact product.
BOXED WARNING ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCER Close clinical surveillance of all women taking estrogens is important.
- Estrogens should not be used in individuals with any of the following conditions: Undiagnosed abnormal genital bleeding.
- Known, suspected or history of cancer of the breast except in appropriately selected patients being treated for metastatic disease.
- Known or suspected estrogen-dependent neoplasia.
- Active deep vein thrombosis, pulmonary embolism or history of these conditions.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
SpainNo exact match for this strength and form
FranceNo exact match for this strength and form
CanadaNo exact match for this strength and form
NetherlandsNo exact match for this strength and form
Details
| Made by | Sandoz Inc |
|---|---|
| Active substance | Estradiol |
| Used in | Urinary and reproductive system, hormones |
| Strength | .0375 mg/d |
| Form | Patch, Extended Release |
| Route | Transdermal |
| Packs | 8 POUCH in 1 CARTON / 1 PATCH in 1 POUCH / 3.5 d in 1 PATCH |
| NDC | 0781-7138 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
143 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Tablet46 products
- Gel36 products
.75 mg/1.25g2
.75 mg/1.25g · 2 companies
1.25 mg/1.25g6
- Patch26 products
.014 mg/d2
.014 mg/d · 2 companies
.025 mg/d4
.0375 mg/d4
.05 mg/d4
.06 mg/d4
.075 mg/d4
.1 mg/d4
- Patch, Extended Release20 products
.025 mg/d4
.0375 mg/d4
.0375 mg/d · 4 companies
- Amneal Pharmaceuticals NY LLC
- Sandoz Inc · this page
- Zydus Lifesciences Limited
- Zydus Pharmaceuticals USA Inc.
.05 mg/d4
.075 mg/d4
.1 mg/d4
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.