Mediclarum
Medicine guide

Icosapent Ethyl

.5 g · Capsule

  • Prescription only
Active substance
Icosapent Ethyl
Made by
Softgel Healthcare Private Limited

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

This information is not included in the verified source. Open the official leaflet

How it works

From the US prescribing label for the same active substance (Icosapent Ethyl). It describes the substance, not this exact product.

Studies suggest that EPA reduces hepatic very low-density lipoprotein triglycerides (VLDL-TG) synthesis and/or secretion and enhances TG clearance from circulating VLDL particles.

Potential mechanisms of action include increased β-oxidation; inhibition of acyl-CoA:1,2-diacylglycerol acyltransferase (DGAT); decreased lipogenesis in the liver; and increased plasma lipoprotein lipase activity.

Peak level after5 h
Half-life89 h
Mostly cleared after≈ 3 weeksfive half-lives — our arithmetic
PeakHalf gone3 weeks0
The shape is a standard model drawn from the two times above, not a measurement. How fast a medicine acts and wears off also depends on the dose, the form and the person.
How the body breaks it down

EPA is mainly metabolized by the liver via beta-oxidation similar to dietary fatty acids.

With food

Icosapent ethyl was administered with or following a meal in all clinical studies; no food effect studies were performed.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-25

Safety of the active substance

From the US prescribing label for the same active substance (Icosapent Ethyl). It describes the substance, not this exact product.

Must not be used by
  • Icosapent ethyl is contraindicated in patients with known hypersensitivity (e.g., anaphylactic reaction) to icosapent ethyl or any of its components.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

European UnionNo exact match for this strength and form

Every strength and form (1)

CanadaNo exact match for this strength and form

Every strength and form (1)

Details

Made bySoftgel Healthcare Private Limited
Active substanceIcosapent Ethyl
Strength.5 g
FormCapsule
RouteOral
Packs240 CAPSULE in 1 BOTTLE
NDC35916-1738

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

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Other strengths and forms

27 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.

Icosapent1000 mgPrescription onlyCapsule Dr. Reddy's Laboratories, Inc. · Icosapent EthylIcosapent1000 mgPrescription onlyCapsule Bryant Ranch Prepack · Icosapent EthylIcosapent Ethyl1 gPrescription onlyCapsule Hikma Pharmaceuticals USA Inc. · Icosapent EthylIcosapent Ethyl.5 gPrescription onlyCapsule Hikma Pharmaceuticals USA Inc. · Icosapent EthylIcosapent Ethyl500 mgPrescription onlyCapsule, Liquid Filled Teva Pharmaceuticals, Inc. · Icosapent EthylIcosapent Ethyl1 gPrescription onlyCapsule, Liquid Filled Teva Pharmaceuticals, Inc. · Icosapent Ethyl

See every product with Icosapent Ethyl