Lacosamide
10 mg/mL · Injection, Solution
- Prescription only
- Controlled substance · CV
- Active substance
- Lacosamide
- Made by
- Sagent Pharmaceuticals
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
This information is not included in the verified source. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Lacosamide Oral Solution). It describes the substance, not this exact product.
The precise mechanism by which Lacosamide oral solution exerts its antiepileptic effects in humans remains to be fully elucidated.
In vitro electrophysiological studies have shown that lacosamide selectively enhances slow inactivation of voltage-gated sodium channels, resulting in stabilization of hyperexcitable neuronal membranes and inhibition of repetitive neuronal firing.
Drug Interactions In Vitro Assessment of Drug Interactions In vitro metabolism studies indicate that lacosamide does not induce the enzyme activity of drug metabolizing cytochrome P450 isoforms CYP1A2, 2B6, 2C9, 2C19 and 3A4.
Metabolism and Elimination Lacosamide oral solution is primarily eliminated from the systemic circulation by renal excretion and biotransformation.
Food does not affect the rate and extent of absorption.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-09-09
Safety of the active substance
From the US prescribing label for the same active substance (Lacosamide Oral Solution). It describes the substance, not this exact product.
Most commonly (≥1% on lacosamide ) leading to discontinuation was dizziness.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
European UnionNo exact match for this strength and form
France6 matching products
CanadaNo exact match for this strength and form
NetherlandsNo exact match for this strength and form
Details
| Made by | Sagent Pharmaceuticals |
|---|---|
| Active substance | Lacosamide |
| Strength | 10 mg/mL |
| Form | Injection, Solution |
| Route | Intravenous |
| Packs | 10 VIAL, GLASS in 1 CARTON / 20 mL in 1 VIAL, GLASS |
| NDC | 25021-791 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
142 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Tablet, Film Coated84 products
- Tablet20 products
- Solution18 products
50 mg/5mL3
50 mg/5mL · 3 companies
100 mg/10mL3
100 mg/10mL · 3 companies
- 150 mg/15mL
- 200 mg/20mL
- Injection15 products
Show all forms · 5 forms
- Injection, Solution5 products
10 mg/mL5
10 mg/mL · 5 companies
- Anthea Pharma Private Limited
- GLENMARK PHARMACEUTICALS INC., USA
- Sagent Pharmaceuticals · this page
- Somerset Therapeutics, LLC
- Virtus Pharmaceuticals, LLC
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.