Memantine Hydrochloride
5 mg · Tablet, Film Coated
- Prescription only
- N-methyl-D-aspartate Receptor Antagonist
- Active substance
- Memantine Hydrochloride
- Made by
- Zydus Lifesciences Limited
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
This information is not included in the verified source. Open the official leaflet
How it works
From the US prescribing label for the same active substance (memantine hydrochloride). It describes the substance, not this exact product.
Persistent activation of central nervous system N-methyl-D-aspartate (NMDA) receptors by the excitatory amino acid glutamate has been hypothesized to contribute to the symptomatology of Alzheimer’s disease.
Memantine is postulated to exert its therapeutic effect through its action as a low to moderate affinity uncompetitive (open-channel) NMDA receptor antagonist which binds preferentially to the NMDA receptor-operated cation channels.
Effect of Memantine Hydrochloride on the Metabolism of Other Drugs In vitro studies conducted with marker substrates of CYP450 enzymes (CYP1A2, -2A6, -2C9, 2D6, -2E1, -3A4) showed minimal inhibition of these enzymes by memantine.
Food has no effect on the absorption of memantine.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2025-12-20
Safety of the active substance
From the US prescribing label for the same active substance (memantine hydrochloride). It describes the substance, not this exact product.
- Memantine hydrochloride tablets are contraindicated in patients with known hypersensitivity to memantine hydrochloride or to any excipients used in the formulation.
Most common adverse reactions (≥ 5 % and greater than placebo) are dizziness, headache, confusion and constipation.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
European UnionNo exact match for this strength and form
Canada2 matching products
Details
| Made by | Zydus Lifesciences Limited |
|---|---|
| Active substance | Memantine Hydrochloride |
| Strength | 5 mg |
| Form | Tablet, Film Coated |
| Route | Oral |
| Packs | 1000 TABLET, FILM COATED in 1 BOTTLE · 100 TABLET, FILM COATED in 1 BOTTLE |
| NDC | 70771-1119 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
103 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Capsule, Extended Release39 products
- Tablet, Film Coated32 products
- Tablet22 products
- Solution4 products
2 mg/mL4
Show all forms · 6 forms
- Tablet, Coated4 products
5 mg2
5 mg · 2 companies
10 mg2
10 mg · 2 companies
- Kit2 products
—2
— · 2 companies
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.