Medicine guide

Metoprolol Succinate Er

25 mg · Tablet, Extended Release

  • Prescription only
  • beta-Adrenergic Blocker
Active substance
Metoprolol Succinate
Made by
Direct_Rx

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupHeart, blood pressure and circulation

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

From the US prescribing label for the same active substance (METOPROLOL TARTRATE). It describes the substance, not this exact product.

Metoprolol is a beta 1 -selective (cardioselective) adrenergic receptor blocking agent.

This preferential effect is not absolute, however, and at higher plasma concentrations, metoprolol also inhibits beta 2 -adrenoreceptors, chiefly located in the bronchial and vascular musculature.

Half-life3–4 h
Mostly cleared after≈ 17.5 hfive half-lives — our arithmetic
How the body breaks it down

Metoprolol tartrate is primarily metabolized by CYP2D6.

How it leaves the body

In most subjects (extensive metabolizers), less than 5% of an oral dose and less than 10% of an intravenous dose are excreted as unchanged drug in the urine.

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-07-27

Safety of the active substance

From the US prescribing label for the same active substance (METOPROLOL TARTRATE). It describes the substance, not this exact product.

Must not be used by
  • Metoprolol tartrate tablets are contraindicated in severe bradycardia, second-or third-degree heart block, cardiogenic shock, systolic blood pressure <100, decompensated heart failure, sick sinus syndrome (unless a permanent pacemaker is in place), and in patients who are hypersensitive to any component of this product..
  • Known hypersensitivity to product components.
  • Severe bradycardia: Greater than first degree heart block, or sick sinus syndrome without a pacemaker.
  • Cardiogenic shock or decompensated heart failure.
Most common side effects

Most common adverse reactions: tiredness, dizziness, depression, shortness of breath, bradycardia, hypotension, diarrhea, pruritus, rash.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

SpainNo exact match for this strength and form

Details

Made byDirect_Rx
Active substanceMetoprolol Succinate
Used inHeart, blood pressure and circulation
Strength25 mg
FormTablet, Extended Release
RouteOral
Packs30 TABLET, EXTENDED RELEASE in 1 BOTTLE · 90 TABLET, EXTENDED RELEASE in 1 BOTTLE
NDC61919-754

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

Other strengths and forms

3 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

  • Tablet, Extended Release2 products
  • Tablet, Film Coated, Extended Release1 products

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.