Mucinex Sinus-Max Day Pressure, Pain and Cough and Mucinex Nightshift Night Sinus Maximum Strength
Kit
- Available without prescription
- Active substance
- Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride, Triprolidine Hydrochloride
- Made by
- Reckitt Benckiser LLC
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
At a glance
Quoted from the official label · 2026-05-12
Active ingredients (in each caplet) Mucinex Sinus-Max Day Pressure, Pain & Cough Purposes Acetaminophen 325 mg Pain reliever Dextromethorphan HBr 10 mg Cough suppressant Guaifenesin 200 mg Expectorant Phenylephrine HCl 5 mg Nasal decongestant Active ingredients (in each caplet) Mucinex Nightshift Night Sinus Purposes Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Phenylephrine HCl 5 mg Nasal decongestant Triprolidine HCl 1.25 mg Antihistamine
- Cough nasal congestion minor aches and pains sore throat headache sneezing sinus congestion and pressure runny nose itching of the nose or throat itchy, watery eyes due to hay fever temporarily reduces fever…
Adults and children 12 years of age and over:: take 2 caplets every 4 hours
do not take more than 12 caplets in any 24-hour period
Full directions ↓With any other drug containing acetaminophen (prescription or nonprescription).
All warnings ↓- Sold without a prescription
- FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02
Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed
What it is for
Mucinex Sinus-Max Day Pressure, Pain & Cough temporarily relieves:
- nasal congestion headache minor aches and pains cough sinus congestion and pressure temporarily promotes nasal and/or sinus drainage helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive Mucinex Nightshift Night Sinus temporarily relieves these common cold and flu symptoms:
- cough nasal congestion minor aches and pains sore throat headache sneezing sinus congestion and pressure runny nose itching of the nose or throat itchy, watery eyes due to hay fever temporarily reduces fever controls cough to help
- you get to sleep
From the official label · 2026-05-12 · DailyMed
Do not take it if
- with any other drug containing acetaminophen (prescription or nonprescription).
- If you are not sure whether a drug contains acetaminophen,
- ask a doctor or pharmacist.
- if you are now taking a prescription monoamine oxidase inhibitor (MAOI) (certain drugs for depression, psychiatric, or emotional conditions, or Parkinson's disease), or for 2 weeks after stopping the MAOI drug.
- If you do not know if your prescription drug contains an MAOI,
- ask a doctor or pharmacist before taking this product.
Quoted from the official label, section “OTC — Do Not Use”.
How to take it
These directions are for this exact strength and form. Another one is different.
- Mucinex Sinus-Max Day Pressure, Pain & Cough
- do not take more than directed (see Overdose warning )
- do not take more than 12 caplets in any 24-hour period
- adults and children 12 years of age and over:
- take 2 caplets every 4 hours
- children under 12 years of age:
- do not use Mucinex Nightshift Night Sinus
- do not take more than directed (see Overdose warning )
- do not take more than 8 caplets in any 24-hour period
- adults and children 12 years of age and over:
- take 2 caplets every 4 hours
- children under 12 years of age:
- do not use
Quoted from the official label, section “Dosage & Administration”.
Ask a doctor first if
liver disease heart disease diabetes high blood pressure thyroid disease glaucoma (Nightshift Night Sinus only) trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis (Nightshift Night Sinus only) persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus)
Quoted from the official label, section “OTC — Ask Doctor”.
Ask a pharmacist first if
you are taking the blood thinning drug warfarin taking sedatives or tranquilizers (Nightshift Night Sinus only)
Quoted from the official label, section “OTC — Ask Doctor/Pharmacist”.
Stop and get help if
- nervousness, dizziness, or sleeplessness occur pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back, or occurs with fever, rash, or headache that lasts.
- These could be signs of a serious condition.
Quoted from the official label, section “OTC — Stop Use”.
Other warnings
- Liver warning This product contains acetaminophen.
- Severe liver damage may occur
- if you take:
- more than 4,000 mg in 24 hours, which is the maximum daily amount with other drugs containing acetaminophen 3 or more alcoholic drinks daily while using this product Allergy alert Acetaminophen may cause severe skin reactions.
- Symptoms may include:
- skin reddening blisters rash If a skin reaction occurs,
- stop use and seek medical help right away.
- Sore throat warning (Nightshift Night Sinus only) If sore throat is severe, persists for more than 2 days, is accompanied or followed by fever, headache, rash, nausea, or vomiting, consult a doctor promptly.
- Do not use with any other drug containing acetaminophen (prescription or nonprescription).
- Ask a doctor before use
- if you have liver disease heart disease diabetes high blood pressure thyroid disease glaucoma (Nightshift Night Sinus only) trouble urinating due to an enlarged prostate gland a breathing problem such as emphysema or chronic bronchitis (Nightshift Night Sinus only) persistent or chronic cough such as occurs with smoking, asthma, chronic bronchitis, or emphysema cough that occurs with too much phlegm (mucus)
- Ask a doctor or pharmacist before use
- if you are taking the blood thinning drug warfarin taking sedatives or tranquilizers (Nightshift Night Sinus only)
- When using this product
- do not use more than directed excitability may occur, especially in children (Nightshift Night Sinus only) marked drowsiness may occur (Nightshift Night Sinus only) alcohol, sedatives, and tranquilizers may increase drowsiness (Nightshift Night Sinus only)
- avoid alcoholic drinks (Nightshift Night Sinus only) use caution when driving a motor vehicle or operating machinery (Nightshift Night Sinus only)
- Stop use and
- ask a doctor if nervousness, dizziness, or sleeplessness occur pain, nasal congestion, or cough gets worse or lasts more than 7 days fever gets worse or lasts more than 3 days redness or swelling is present new symptoms occur cough comes back, or occurs with fever, rash, or headache that lasts.
- Keep out of reach of children.
- Overdose warning Taking more than the recommended dose (overdose) may cause liver damage.
- In case of overdose, get medical help or contact a Poison Control Center right away.
- Quick medical attention is critical for
- adults as well as for children even
- if you do not notice any signs or symptoms.
- do not use more than directed excitability may occur, especially in children (Nightshift Night Sinus only) marked drowsiness may occur (Nightshift Night Sinus only) alcohol, sedatives, and tranquilizers may increase drowsiness (Nightshift Night Sinus only)
- avoid alcoholic drinks (Nightshift Night Sinus only) use caution when driving a motor vehicle or operating machinery (Nightshift Night Sinus only)
Quoted from the official label, section “Warnings”.
Pregnancy and breastfeeding
If pregnant or breast-feeding, ask a health professional before use.
Quoted from the official label, section “OTC — Pregnancy or Breast Feeding”.
How to store it
store at 20-25°C (68-77°F)
Quoted from the official label, section “Storage and Handling”.
What kind of medicine it is
Active ingredients (in each caplet) Mucinex Sinus-Max Day Pressure, Pain & Cough Purposes Acetaminophen 325 mg Pain reliever Dextromethorphan HBr 10 mg Cough suppressant Guaifenesin 200 mg Expectorant Phenylephrine HCl 5 mg Nasal decongestant Active ingredients (in each caplet) Mucinex Nightshift Night Sinus Purposes Acetaminophen 325 mg Pain reliever/fever reducer Dextromethorphan HBr 10 mg Cough suppressant Phenylephrine HCl 5 mg Nasal decongestant Triprolidine HCl 1.25 mg Antihistamine
Quoted from the official label, section “OTC — Purpose”.
Other ingredients
Relevant if you react to a dye, a preservative, lactose or gluten.
- Mucinex Sinus-Max Day Pressure, Pain & Cough croscarmellose sodium, crospovidone, FD&C red no. 40 aluminum lake, FD&C yellow no. 6 aluminum lake, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polyvinyl alcohol, povidone, talc, titanium dioxide
- Mucinex Nightshift Night Sinus croscarmellose sodium, crospovidone, ferric oxide, hydroxypropyl cellulose, mica, microcrystalline cellulose, polyvinyl alcohol, polyvinyl alcohol polyethylene glycol copolymer, povidone, silicon dioxide, stearic acid, talc, titanium dioxide
Quoted from the official label, section “Inactive Ingredients”.
Questions about this product
1-866-MUCINEX (1-866-682-4639) You may also report side effects to this phone number.
Quoted from the official label, section “OTC — Questions”.
Ingredients people check for
Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.
- Colour dyes
FD&C red no. 40 aluminum lake; FD&C yellow no. 6 aluminum lake
Some people react to dyes such as tartrazine (Yellow 5) or carmine. - Titanium dioxide
titanium dioxide Inactive ingredients Mucinex Nightshift Night Sinus croscarmellose sodium; titanium dioxide
A whitening agent no longer allowed in food in the EU (E171).
Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.
Details
| Made by | Reckitt Benckiser LLC |
|---|---|
| Active substance | Acetaminophen, Dextromethorphan Hydrobromide, Guaifenesin, Phenylephrine Hydrochloride, Triprolidine Hydrochloride |
| Form | Kit |
| Packs | 1 KIT in 1 CARTON / 1 KIT in 1 KIT * 6 TABLET, FILM COATED in 1 BLISTER PACK * 4 TABLET, COATED in 1 BLISTER PACK · 2 KIT in 1 CARTON / 1 KIT in 1 KIT * 6 TABLET, FILM COATED in 1 BLISTER PACK * 4 TABLET, COATED in 1 BLISTER PACK |
| NDC | 72854-243 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).