Pregabalin
300 mg · Capsule
- Prescription only
- Controlled substance · CV
- Active substance
- Pregabalin
- Made by
- MARKSANS PHARMA LIMITED
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Pregabalin). It describes the substance, not this exact product.
Pregabalin binds with high affinity to the alpha 2 -delta site (an auxiliary subunit of voltage-gated calcium channels) in central nervous system tissues.
Although the mechanism of action of pregabalin has not been fully elucidated, results with genetically modified mice and with compounds structurally related to pregabalin (such as gabapentin) suggest that binding to the alpha 2 -delta subunit may be involved in pregabalin’s anti-nociceptive and antiseizure effects in animals.
Therefore, an increase in the metabolism of coadministered CYP1A2 substrates (e.g. theophylline, caffeine) or CYP 3A4 substrates (e.g., midazolam, testosterone) is not anticipated.
The rate of pregabalin absorption is decreased when given with food, resulting in a decrease in C max of approximately 25% to 30% and an increase in T max to approximately 3 hours.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-04-07
Safety of the active substance
From the US prescribing label for the same active substance (Pregabalin). It describes the substance, not this exact product.
- Pregabalin is contraindicated in patients with known hypersensitivity to pregabalin or any of its components.
- Angioedema and hypersensitivity reactions have occurred in patients receiving pregabalin therapy [see Warnings and Precautions (5.2) ].
- Known hypersensitivity to pregabalin or any of its components.
Most common adverse reactions (greater than or equal to 5% and twice placebo) in pediatric patients for the treatment of partial-onset seizures are increased weight and increased appetite.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
Bulgaria2 matching products
European UnionNo exact match for this strength and form
Details
| Made by | MARKSANS PHARMA LIMITED |
|---|---|
| Active substance | Pregabalin |
| Strength | 300 mg |
| Form | Capsule |
| Route | Oral |
| Packs | 90 CAPSULE in 1 BOTTLE |
| NDC | 25000-186 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
334 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Capsule325 products
- Tablet, Film Coated, Extended Release6 products
82.5 mg2
82.5 mg · 2 companies
165 mg2
165 mg · 2 companies
330 mg2
330 mg · 2 companies
- Solution3 products
20 mg/mL3
20 mg/mL · 3 companies
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.