Medicine guide

Unblemish Invisible Matte Defense

.1 g/mL + .1 g/mL + .05 g/mL + .03 g/mL · Gel

  • Available without prescription
Made by
Rodan & Fields

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

At a glance

Quoted from the official label · 2023-11-27

What it is

Sunscreen

Used for
  • Helps prevent sunburn. When used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun.
Do not take it if

On damaged or broken skin.

All warnings ↓
Good to know
  • Sold without a prescription
  • FDA enforcement reports list no ongoing recall, and none from the last two years, for this product code · checked 2026-10-02
52other products contain Homosalate, Octocrylene, Octisalate, Avobenzone — compare makers, forms and strengths

Every line above is selected, not written, from the official label. Nothing is reworded. DailyMed

What it is for

  • Helps prevent sunburn. When used as directed with other sun protection measures (see Directions ), decreases the risk of skin cancer and early skin aging caused by the sun.

From the official label · 2023-11-27 · DailyMed

Do not take it if

on damaged or broken skin.

Quoted from the official label, section “OTC — Do Not Use”.

How to take it

These directions are for this exact strength and form. Another one is different.

  • Apply liberally over entire face at least 15 minutes before sun exposure.
  • Reapply at least every 2 hours.
  • Use a water-resistant sunscreen if swimming or sweating.
  • Sun Protection Measures.
  • Spending time in the sun increases your risk of skin cancer and early skin aging.
  • To decrease this risk, regularly use a sunscreen with broad spectrum SPF value of 15 or higher and other sun protection measures including:
  • Limit time in the sun, especially from 10 a.m.-2 p.m.
  • Wear long-sleeve shirts, pants, hats and sunglasses.
  • Children under 6 months: ask a doctor.

Quoted from the official label, section “Dosage & Administration”.

Stop and get help if

and ask doctor if rash occurs.

Quoted from the official label, section “OTC — Stop Use”.

Other warnings

  • For external use only
  • Do not use on damaged or broken skin.
  • When using this product
  • keep out of eyes. Rinse with water to remove.
  • Stop use and ask doctor if rash occurs.
  • Keep out of reach of children. If swallowed, get medical help right away.
  • keep out of eyes. Rinse with water to remove.

Quoted from the official label, section “Warnings”.

Keep away from children

If swallowed, get medical help right away.

Quoted from the official label, section “OTC — Keep Out of Reach of Children”.

Other information

Protect this product from excessive heat and direct sun.

Quoted from the official label, section “OTC — Other Information”.

What kind of medicine it is

Sunscreen

Quoted from the official label, section “OTC — Purpose”.

Other ingredients

Relevant if you react to a dye, a preservative, lactose or gluten.

lsododecane, Dimethicone Crosspolymer, Dimethicone/Bis-lsobutyl PPG-20 Crosspolymer, Butyloctyl Salicylate, Silica, C12-15 Alkyl Benzoate, Polysilicone-22, Glycerin, Linoleic Acid, Linolenic Acid, Oleic Acid, Palmitic Acid, Vinyl Dimethicone/Methicone Silsesquioxane Crosspolymer, Divinyldimethicone/Dimethicone/Phenylsilsesquioxane Crosspolymer, Polymethylsilsesquioxane, Silica Silylate, Stearic Acid, Tocopherol, Ethylhexylglycerin, Benzyl Alcohol

Quoted from the official label, section “Inactive Ingredients”.

Questions about this product

1-888-995-5656

Quoted from the official label, section “OTC — Questions”.

Ingredients people check for

Lactose, gluten, dyes, sugars and other ingredients that matter with an allergy, intolerance or diet — as this product’s FDA label lists them.

This label’s list of inactive ingredients names none of: lactose, wheat or gluten, colour dyes, sugars, sugar alcohols, alcohol (ethanol), aspartame (phenylalanine), gelatin, peanut oil, soy, parabens, sulfites, titanium dioxide.

Quoted from the FDA label. A label that does not name an ingredient is not a guarantee that the product is free of it, and formulations change. With an allergy, check the pack and ask a pharmacist.

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

CanadaNo exact match for this strength and form

Details

Made byRodan & Fields
Active substanceHomosalate, Octocrylene, Octisalate, Avobenzone
Strength.1 g/mL + .1 g/mL + .05 g/mL + .03 g/mL
FormGel
RouteTopical
Packs1 TUBE in 1 CARTON / 30 mL in 1 TUBE · 1 TUBE in 1 CARTON / 7 mL in 1 TUBE
NDC14222-2131

Source: NDC Directory · 2026-09-13 · not reviewed by a clinician

Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.