Vardenafil Hydrochloride
2.5 mg · Tablet, Film Coated
- Prescription only
- Phosphodiesterase 5 Inhibitor
- Active substance
- Vardenafil Hydrochloride
- Made by
- Alembic Pharmaceuticals Limited
- Source
- Official label
Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.
What it is for
Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet
How it works
From the US prescribing label for the same active substance (Vardenafil Hydrochloride). It describes the substance, not this exact product.
Penile erection is a hemodynamic process initiated by the relaxation of smooth muscle in the corpus cavernosum and its associated arterioles.
During sexual stimulation, nitric oxide is released from nerve endings and endothelial cells in the corpus cavernosum.
Vardenafil is metabolized predominantly by the hepatic enzyme CYP3A4, with contribution from the CYP3A5 and CYP2C isoforms.
After oral administration, vardenafil is excreted as metabolites predominantly in the feces (approximately 91-95% of administered oral dose) and to a lesser extent in the urine (approximately 2-6% of administered oral dose).
Two food-effect studies were conducted which showed that high- fat meals caused a reduction in C max by 18%-50%.
Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-08-27
Safety of the active substance
From the US prescribing label for the same active substance (Vardenafil Hydrochloride). It describes the substance, not this exact product.
- Administration with nitrates and nitric oxide donors ( 2.4, 4.1 ) Administration with guanylate cyclase (GC) stimulators, such as riociguat ( 2.4, 4.2 ) 4.1 Nitrates Administration of vardenafil hydrochloride tablets with nitrates (either regularly and/or intermittently) and nitric oxide donors is contraindicated [see Clinical Pharmacology (12.2) ].
- Consistent with the effects of PDE5 inhibition on the nitric oxide/cyclic guanosine monophosphate pathway, PDE5 inhibitors, including vardenafil hydrochloride tablets, may potentiate the hypotensive effects of nitrates.
- A suitable time interval following dosing of vardenafil hydrochloride tablets for the safe administration of nitrates or nitric oxide donors has not been determined. 4.2 Guanylate Cyclase (GC) Stimulators Do not use vardenafil hydrochloride tablets in patients who are using a GC stimulator, such as riociguat.
- PDE5 inhibitors, including vardenafil hydrochloride tablets may potentiate the hypotensive effects of GC stimulators.
Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed
Same active substance, strength and form in other countries
Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.
Medicine passport: one printable page to show a pharmacist abroad
BulgariaNo exact match for this strength and form
European UnionNo exact match for this strength and form
Details
| Made by | Alembic Pharmaceuticals Limited |
|---|---|
| Active substance | Vardenafil Hydrochloride |
| Used in | Urinary and reproductive system, hormones |
| Strength | 2.5 mg |
| Form | Tablet, Film Coated |
| Route | Oral |
| Packs | 30 TABLET, FILM COATED in 1 BOTTLE · 100 TABLET, FILM COATED in 1 BOTTLE |
| NDC | 46708-236 |
Source: NDC Directory · 2026-09-13 · not reviewed by a clinician
Source: US Food and Drug Administration, NDC Directory. Reuse terms: US government work (FDA).
Other strengths and forms
28 products are sold under this name. Grouped by form; a number on a strength means several companies make it.
- Tablet15 products
2.5 mg3
2.5 mg · 3 companies
5 mg3
5 mg · 3 companies
10 mg4
- Tablet, Film Coated13 products
2.5 mg3
2.5 mg · 3 companies
- Alembic Pharmaceuticals Inc.
- Alembic Pharmaceuticals Limited · this page
- Teva Pharmaceuticals USA, Inc.
5 mg3
10 mg3
Same active substance
These contain the same substance. That does not mean one can replace another — ask a pharmacist.