Medicine guide

PAVBLU

As listed in the register: PAVBLU 40 MG/ML SOLUCION INYECTABLE EN JERINGA PRECARGADA

40 mg/ml · solución inyectable

  • Prescription only
  • Eyes and ears
Active substance
Aflibercept
Made by
Amgen Technology (Ireland) Unlimited Company

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupEyes and earsS01LA05

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

From the US prescribing label for the same active substance (EYLEA). It describes the substance, not this exact product.

Vascular endothelial growth factor-A (VEGF-A) and placental growth factor (PlGF) are members of the VEGF family of angiogenic factors that can act as mitogenic, chemotactic, and vascular permeability factors for endothelial cells.

VEGF acts via two receptor tyrosine kinases, VEGFR-1 and VEGFR-2, present on the surface of endothelial cells.

Half-life5–6 days
Mostly cleared after≈ 4 weeksfive half-lives — our arithmetic

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-07-07

Safety of the active substance

From the US prescribing label for the same active substance (EYLEA). It describes the substance, not this exact product.

Must not be used by
  • Hypersensitivity reactions may manifest as rash, pruritus, urticaria, severe anaphylactic/anaphylactoid reactions, or severe intraocular inflammation.
Most common side effects

The most common adverse reactions (≥5%) reported in patients receiving EYLEA were conjunctival hemorrhage, eye pain, cataract, vitreous detachment, vitreous floaters, and intraocular pressure increased.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

European UnionNo exact match for this strength and form

CanadaNo exact match for this strength and form

SwitzerlandNo exact match for this strength and form

Details

Made byAmgen Technology (Ireland) Unlimited Company
Active substanceAflibercept
Used inEyes and ears
Strength40 mg/ml
Formsolución inyectable
ClassificationS01LA05 · Eyes and ears
Routevía intravítrea
MarketedNo — authorised but not currently marketed, according to the register
BiosimilarYes — a biosimilar medicine, according to the register
Additional monitoring ▼Yes — under additional monitoring (black triangle). Report suspected side effects.
DrivingThe regulator flags that this medicine can affect the ability to drive.
Name in the registerPAVBLU 40 MG/ML SOLUCION INYECTABLE EN JERINGA PRECARGADA
Nº Registro1251909001

Source: CIMA — Centro de Información online de Medicamentos · 2026-09-30 · not reviewed by a clinician

Fuente: Agencia Española de Medicamentos y Productos Sanitarios (AEMPS), CIMA. Reuse terms: Aviso legal AEMPS.

Other strengths and forms

2 products are sold under this name. Grouped by form; a number on a strength means several companies make it.

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.