Medicine guide

Afqlir 40 mg/ml oplossing voor injectie in een injectieflacon

As listed in the register: Afqlir 40 mg/ml oplossing voor injectie in een injectieflacon

40 mg/ml · oplossing voor injectie

  • Prescription only
  • Eyes and ears
Active substance
Aflibercept
Made by
Sandoz GmbH

Quoted from the official source. Not yet reviewed by Mediclarum — the leaflet in your pack is authoritative.

What it is for

Medicine groupEyes and earsS01LA05

Mediclarum has not yet retrieved and stored the official label for this product, so none of its text is shown here. Open the official leaflet

How it works

From the US prescribing label for the same active substance (EYLEA). It describes the substance, not this exact product.

Vascular endothelial growth factor-A (VEGF-A) and placental growth factor (PlGF) are members of the VEGF family of angiogenic factors that can act as mitogenic, chemotactic, and vascular permeability factors for endothelial cells.

VEGF acts via two receptor tyrosine kinases, VEGFR-1 and VEGFR-2, present on the surface of endothelial cells.

Half-life5–6 days
Mostly cleared after≈ 4 weeksfive half-lives — our arithmetic

Quoted from the prescribing label, sections “Mechanism of Action” and “Pharmacokinetics”. DailyMed · 2026-07-07

Safety of the active substance

From the US prescribing label for the same active substance (EYLEA). It describes the substance, not this exact product.

Must not be used by
  • Hypersensitivity reactions may manifest as rash, pruritus, urticaria, severe anaphylactic/anaphylactoid reactions, or severe intraocular inflammation.
Most common side effects

The most common adverse reactions (≥5%) reported in patients receiving EYLEA were conjunctival hemorrhage, eye pain, cataract, vitreous detachment, vitreous floaters, and intraocular pressure increased.

Quoted from the US prescribing label for the same active substance. Your own pack’s leaflet is the authority for your product. DailyMed

Same active substance, strength and form in other countries

Matched on active substance, strength and kind of form only. This is not a statement that the products are equivalent or interchangeable: other ingredients, release and approved uses can differ — ask a pharmacist before swapping.

Medicine passport: one printable page to show a pharmacist abroad

European UnionNo exact match for this strength and form

CanadaNo exact match for this strength and form

SwitzerlandNo exact match for this strength and form

Details

Made bySandoz GmbH
Active substanceAflibercept
Used inEyes and ears
Strength40 mg/ml
Formoplossing voor injectie
ClassificationS01LA05 · Eyes and ears
Routeintravitreaal gebruik
Dispensing (as stated by the register)Uitsluitend recept
RVGEU/1/24/1867

Source: Geneesmiddeleninformatiebank · 2026-09-30 · not reviewed by a clinician

Bron: College ter Beoordeling van Geneesmiddelen (CBG). De Rijksoverheid is het niet automatisch eens met de inhoud van deze site. Reuse terms: CC0 1.0 (CBG website).

Same active substance

These contain the same substance. That does not mean one can replace another — ask a pharmacist.